BREAST NEOPLASM
Clinical trials for BREAST NEOPLASM explained in plain language.
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New hope for advanced breast cancer: drug combo shows promise after standard treatment fails
Disease control OngoingThis study tests whether adding abemaciclib to fulvestrant can help people with a certain type of advanced breast cancer (HR+, HER2-) that has gotten worse after initial treatment with a CDK4/6 inhibitor and hormone therapy. About 368 participants will receive either the drug com…
Matched conditions: BREAST NEOPLASM
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 16, 2026 23:50 UTC
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Heart-Sparing proton therapy tested in advanced breast cancer
Disease control OngoingThis study tests a precise type of radiation called proton therapy given after surgery for stage II/III breast cancer. The goal is to see if it can effectively treat cancer while reducing damage to the heart and other organs. About 220 women will receive this treatment and be fol…
Matched conditions: BREAST NEOPLASM
Phase: PHASE2 • Sponsor: Proton Collaborative Group • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hope for advanced breast cancer: drug combo tested after chemo fails
Disease control OngoingThis study tests a drug called trifluridine/tipiracil in 52 women with advanced ER-positive, HER2-negative breast cancer that can't be cured with surgery or radiation. Participants had already received certain chemotherapies. The goal is to see if the drug can slow cancer growth …
Matched conditions: BREAST NEOPLASM
Phase: PHASE2 • Sponsor: Borstkanker Onderzoek Groep • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New PET tracer could reveal hidden breast cancer activity
Knowledge-focused OngoingThis study tests a special PET scan tracer called [18F]ISO-1 to see if it can detect sigma-2 receptors in breast cancer tumors. About 30 adults with known or suspected breast cancer will receive the tracer and undergo imaging. The goal is to see if the tracer's uptake matches tum…
Matched conditions: BREAST NEOPLASM
Phase: PHASE1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 16, 2026 23:50 UTC
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New study tracks nerve pain from breast cancer drug
Knowledge-focused OngoingThis study follows 36 people with HER2-positive breast cancer who are receiving the drug T-DM1. The goal is to learn how often and how severely nerve damage (peripheral neuropathy) occurs, and how it changes over time. Participants fill out questionnaires about their symptoms, an…
Matched conditions: BREAST NEOPLASM
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Can a website help cancer patients protect their fertility?
Knowledge-focused OngoingThis study looks at whether a special website can help women with cancer make better decisions about preserving their ability to have children after treatment. About 130 women with certain cancers (like breast or lymphoma) will use the website or get usual care. The goal is to se…
Matched conditions: BREAST NEOPLASM
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC
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New imaging technique could reveal how breast cancer drugs work inside the body
Knowledge-focused OngoingThis study uses a special type of PET/CT scan called FLT to see how active breast cancer tumors are before and during treatment with two drugs (ribociclib and paclitaxel). About 20 adults with metastatic breast cancer that has spread beyond the liver and bones will take part. The…
Matched conditions: BREAST NEOPLASM
Phase: PHASE1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC