New radiation technique aims to spare heart in breast cancer patients

NCT ID NCT01758445

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing a precise type of radiation called proton therapy for women with stage II or III breast cancer who need radiation to the whole breast or chest wall and lymph nodes. The goal is to see if this approach causes fewer side effects, especially to the heart, compared to standard radiation. About 220 participants will be followed for up to 15 years to track heart health and risk of new cancers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Proton radiotherapy

What this could lead to

If successful, this could offer a safer radiation option for advanced breast cancer, lowering the risk of heart problems and second cancers later in life.

What could go wrong

This is a mid-stage trial with 220 participants, so results are not yet proven. Long-term benefits and risks (like heart issues or new cancers) will take 10-15 years to fully assess.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hampton University Proton Therapy Institute

    Hampton, Virginia, 23666, United States

  • Maryland Proton Treatment Center

    Baltimore, Maryland, 21201, United States

  • Northwestern Medicine Chicago Proton Center

    Warrenville, Illinois, 60555, United States

  • Oklahoma Proton Center

    Oklahoma City, Oklahoma, 73142, United States

  • Princeton ProCure Managment LLC

    Somerset, New Jersey, 08873, United States