New scan could reveal if breast cancer drugs are working in days

NCT ID NCT02608216

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase study tests whether a special PET scan using a tracer called FLT can show how breast cancer tumors respond to a combination of two drugs, ribociclib and paclitaxel. The study involves 20 people with metastatic breast cancer that has spread beyond the liver and bone. Researchers will take scans before and during treatment to see if changes in tumor activity can predict whether the therapy is working.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ribociclib (LEE011) and paclitaxel

What this could lead to

If successful, this imaging method could help doctors quickly tell if a breast cancer treatment is working, potentially guiding more personalized therapy.

What could go wrong

This is a very small, early-phase study focused on imaging, not on proving the treatment works. The results may not apply to all patients or lead to a direct benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast carcinoma breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pennsylvania Hospital

    Philadelphia, Pennsylvania, 19104, United States