Simple exercise trick may shield cancer patients from chemo nerve pain

NCT ID NCT04652609

Recruiting now Prevention Sponsor: Universidad de Granada Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special exercise program, called PRESIONA, can prevent nerve damage (peripheral neuropathy) caused by chemotherapy in breast cancer patients. The program combines aerobic and strength exercises with blood flow restriction cuffs. Researchers will compare 25 patients doing this program to those receiving usual care, measuring nerve symptoms and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: therapeutic exercise combined with blood flow restriction
What this could lead to: If it works, this could offer a drug-free way to prevent painful nerve damage caused by chemotherapy, improving quality of life for breast cancer patients.
What could go wrong: This is a very small early study (25 people) with no comparison to other prevention methods. The exercise program may be hard to follow, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

breast neoplasm HER2 positive breast carcinoma Small Fiber Neuropathy chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASM

Contacts and locations

Locations

University of Granada
RECRUITING

Granada, 18016, Spain

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