BIPOLAR I DISORDER
Clinical trials for BIPOLAR I DISORDER explained in plain language.
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New hope for Long-Term bipolar depression treatment
Disease control ENROLLING_BY_INVITATIONThis study aims to understand the long-term safety and effectiveness of the drug azetukalner for adults with bipolar depression. It is open to 400 participants who successfully completed a previous Phase 3 trial of the same drug. The main goal is to monitor side effects and see i…
Matched conditions: BIPOLAR I DISORDER
Phase: PHASE3 • Sponsor: Xenon Pharmaceuticals Inc. • Aim: Disease control
Last updated Apr 02, 2026 01:11 UTC
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Kids' mental health drug gets extended safety check
Disease control ENROLLING_BY_INVITATIONThis study follows children and teenagers with schizophrenia or bipolar I disorder who are already taking OLZ/SAM medication to check for long-term safety. Researchers want to see if side effects develop when patients take this drug combination for an extended period. The study i…
Matched conditions: BIPOLAR I DISORDER
Phase: PHASE3 • Sponsor: Alkermes, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Major trial aims to crack the code on bipolar depression treatment
Disease control OngoingThis large study aims to find the best medication strategies for adults with bipolar disorder who are experiencing a depressive episode. It will compare four common treatment approaches, including three FDA-approved medications and one widely used combination. If a person's first…
Matched conditions: BIPOLAR I DISORDER
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Can exercise speed recovery from bipolar depression?
Symptom relief TerminatedThis study is testing if adding supervised aerobic exercise to standard medication helps people with bipolar depression recover faster and prevents future episodes. It will involve 54 participants who are randomly assigned to either an exercise group, a relaxation group, or an in…
Matched conditions: BIPOLAR I DISORDER
Phase: NA • Sponsor: Region Stockholm • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Scientists scan brains to unlock clues for treating bipolar depression
Knowledge-focused OngoingThis study aims to understand how a magnetic stimulation treatment affects the brain in older adults with bipolar depression. Researchers will use brain scans before and after treatment to measure changes in brain activity. The goal is to gather information that could help guide …
Matched conditions: BIPOLAR I DISORDER
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Researchers seek better way to gauge mental health crises
Knowledge-focused OngoingThis study aims to see if questionnaires filled out by patients and their close contacts (like family members) during episodes of severe agitation match up with ratings from doctors. It involves about 30 adults with schizophrenia or bipolar disorder and their chosen informant. Th…
Matched conditions: BIPOLAR I DISORDER
Phase: PHASE2 • Sponsor: BioXcel Therapeutics Inc • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC