Can a ketamine shot stop suicidal thoughts in minutes?
NCT ID NCT04640636
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a single injection of ketamine can quickly reduce suicidal thoughts in people with depression who come to the emergency room. About 90 participants will receive either ketamine or a sedative (midazolam) and be monitored for 24 hours. The trial is currently paused due to a research suspension at the study site.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine hydrochloride injection
What this could lead to
If it works, this could provide a fast, easy-to-use treatment for suicidal thoughts in emergency rooms.
What could go wrong
The trial is currently suspended due to a research pause, so results are delayed. It is a small, early-phase study, and ketamine may cause side effects like dissociation or increased blood pressure.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Comprehensive Psychiatric Emergency Department of Columbia University Medical Center
New York, New York, 10032, United States