New electric therapy may ease depression without memory loss

NCT ID NCT05172271

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study tests a new treatment called TEST for people with depression that hasn't improved with standard treatments. TEST uses a weaker electric current than standard electroconvulsive therapy (ECT), aiming to reduce side effects like memory problems. Eight adults aged 25-64 will receive TEST or a sham (fake) treatment to see if it is safe, feasible, and helpful for depression.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.