BIPOLAR DISORDER
Clinical trials for BIPOLAR DISORDER explained in plain language.
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Bipolar drug safety trial halted early
Disease control TerminatedThis study tested the long-term safety of the drug BHV-7000 in 94 adults with bipolar I disorder. Participants had to have finished an earlier study first. The trial was stopped early, and researchers tracked side effects like lab abnormalities and heart changes. The goal was to …
Matched conditions: BIPOLAR DISORDER
Phase: PHASE2 • Sponsor: Biohaven Therapeutics Ltd. • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New combo therapy shows promise for stubborn depression
Symptom relief TerminatedThis study tested whether adding a type of talk therapy (behavioral activation) to esketamine treatment helps people with depression that hasn't improved with standard medications. Six adults with major depression or bipolar disorder took part. The goal was to see if practicing n…
Matched conditions: BIPOLAR DISORDER
Phase: NA • Sponsor: The Royal's Institute of Mental Health Research • Aim: Symptom relief
Last updated Apr 30, 2026 15:50 UTC
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Brain scan study seeks clues to bipolar disorder
Knowledge-focused TerminatedThis study aimed to compare brain wiring in people with bipolar disorder (both treatment-resistant and treatment-responsive) and healthy volunteers using special MRI scans. Researchers hoped to find differences in brain pathways that could guide future treatments. The study was t…
Matched conditions: BIPOLAR DISORDER
Sponsor: Jennifer Sweet • Aim: Knowledge-focused
Last updated May 17, 2026 00:42 UTC
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Heart risk check for antipsychotic users
Knowledge-focused TerminatedThis study looked at heart disease risk in 48 adults with schizophrenia, schizoaffective disorder, or bipolar disorder who were taking antipsychotic medications. Researchers measured blood fat ratios and heart electrical activity to understand how these drugs affect cardiovascula…
Matched conditions: BIPOLAR DISORDER
Phase: PHASE3 • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Smartphone study aims to curb veteran suicide by boosting emotional awareness
Knowledge-focused TerminatedThis study tested a smartphone-based program to help veterans with serious mental illness (like PTSD, bipolar disorder, or schizophrenia) who struggle to recognize their own emotions—a condition called alexithymia. The goal was to see if improving emotion awareness could lower su…
Matched conditions: BIPOLAR DISORDER
Phase: PHASE1 • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 06, 2026 16:13 UTC