Brain scan study aims to map bipolar Disorder's hidden pathways
NCT ID NCT05186077
First seen Jun 25, 2026 · Last updated Jul 07, 2026 · Updated 3 times
Summary
This study used MRI brain scans to look at the brain's white matter connections in people with bipolar disorder. Researchers compared those whose illness responds to treatment with those who do not respond, as well as healthy volunteers. The goal was to find brain differences that could one day lead to new treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could help identify brain targets for future treatments for bipolar disorder.
- What could go wrong
- The study was terminated early with only 26 participants, so results may be limited and not generalizable. It was an observational imaging study, not a treatment trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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