ATYPICAL TERATOID/RHABDOID TUMOR
Clinical trials for ATYPICAL TERATOID/RHABDOID TUMOR explained in plain language.
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New pill combo offers hope for kids with relapsed cancers
Disease control Recruiting nowThis study tests two oral drugs, eflornithine (DFMO) and AMXT 1501, in children and young adults up to age 26 with certain cancers that have come back or not responded to treatment. The cancers include neuroblastoma, brain tumors, and sarcomas. The goal is to find a safe dose and…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jul 02, 2026 02:00 UTC
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New hope for toddlers with aggressive brain cancer: experimental spinal-fluid chemo
Disease control Recruiting nowThis early-phase study tests whether adding chemotherapy directly into the spinal fluid (intrathecal topotecan) followed by maintenance pills is feasible for children under 6 with high-risk embryonal brain tumors. About 15 children will receive this treatment after standard high-…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: EARLY_PHASE1 • Sponsor: C17 Council • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Killer virus turned against childhood brain cancer
Disease control Recruiting nowThis early-stage trial tests whether a specially engineered herpes virus (G207) is safe to inject directly into the brain tumors of children whose cancer has returned. Up to 24 children aged 3 to 21 will receive the virus, and some will also get a small dose of radiation to help …
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Engineered immune cells delivered directly to the brain show promise for kids with deadly tumors
Disease control Recruiting nowThis early-stage trial tests a new treatment for children and young adults up to age 21 with certain brain tumors that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack a pro…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Ultrasound 'Key' may let chemo reach Kids' brain tumors
Disease control Recruiting nowThis early-stage trial tests whether a device called SonoCloud-9 can safely open the blood-brain barrier in children aged 5 to 17 with recurrent malignant brain tumors. The barrier normally blocks chemotherapy from reaching the brain. By using low-intensity ultrasound just before…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Engineered t cells take on deadly brain cancers
Disease control Recruiting nowThis early-phase trial tests a new type of immune therapy for people with certain aggressive brain tumors, including DIPG and high-grade glioma. The treatment uses the patient's own T cells, which are modified in the lab to recognize a protein called GD2 on cancer cells and to pr…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Engineered immune cells take aim at childhood brain cancers
Disease control Recruiting nowThis early-phase study tests whether a new type of immunotherapy, called B7-H3 CAR T cells, can be safely given directly into the brain or spinal fluid of children and young adults with aggressive brain tumors like DIPG, DMG, or other recurrent central nervous system cancers. The…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Experimental drug DFMO offered to kids with rare cancers
Disease control AVAILABLEThis expanded access program provides the drug DFMO to children and young adults up to age 30 with rare relapsed tumors such as neuroblastoma or medulloblastoma. The goal is to control the disease by targeting specific genetic markers. Participants take DFMO by mouth twice daily,…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Sponsor: Giselle Sholler • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC