ATYPICAL TERATOID/RHABDOID TUMOR
Clinical trials for ATYPICAL TERATOID/RHABDOID TUMOR explained in plain language.
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New hope for rare childhood cancers: immunotherapy combo shows promise
Disease control OngoingThis study tests two immunotherapy drugs, tiragolumab and atezolizumab, in children and adults whose rare cancers (like atypical teratoid/rhabdoid tumors or epithelioid sarcoma) have returned or not responded to treatment. These cancers lack certain genes, making them hard to tre…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 03:11 UTC
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Promising drug targets rare childhood brain and kidney tumors
Disease control OngoingThis study tests a drug called alisertib in children and young adults under 22 with rare, aggressive tumors of the brain (AT/RT) or kidney (MRT). For those whose cancer has returned or not responded, alisertib is given alone. For newly diagnosed patients, it is combined with chem…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope for kids with rare cancers: Three-Drug combo under study
Disease control OngoingThis study tests a combination of three drugs—tazemetostat, nivolumab, and ipilimumab—for children with rare tumors that lack certain proteins (INI1 or SMARCA4). The goal is to find safe doses and see if the drugs shrink tumors. About 49 children with specific cancers like atypic…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Susan Chi, MD • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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Immunotherapy duo takes on rare childhood tumors
Disease control OngoingThis study tests whether combining two immunotherapy drugs, nivolumab and ipilimumab, can shrink or control rare INI1-negative cancers in children and young adults. These cancers have returned or not responded to standard treatments. The goal is to see if the drug combo helps the…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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Engineered immune cells injected directly into brain show promise for kids with cancer
Disease control OngoingThis early-stage study tests whether specially engineered immune cells (CAR T cells) can be safely given directly into the brain or spinal fluid of children and young adults with HER2-positive brain tumors that have come back or not responded to standard treatments. The cells are…
Matched conditions: ATYPICAL TERATOID/RHABDOID TUMOR
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 11, 2026 20:40 UTC