Promising drug targets rare childhood tumors in phase 2 trial
NCT ID NCT02114229
First seen Mar 22, 2026 · Last updated Apr 28, 2026 · Updated 3 times
Summary
This study tests a drug called alisertib in children and young adults under 22 with rare, aggressive tumors of the brain (AT/RT) or kidney (MRT). For those whose cancer has returned, alisertib is given alone. For newly diagnosed patients, it is combined with chemotherapy and sometimes radiation. The goal is to see if the drug can shrink tumors or stop them from growing, and to find the best way to use it in these hard-to-treat cancers.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital and Clinics of Minnesota
Minneapolis, Minnesota, 55102, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Lucille Packard Children's Hospital at Stanford University Medical Center
Palo Alto, California, 94304, United States
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Rady Children's Hospital
San Diego, California, 92123, United States
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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UF Cancer Center at Orlando Health
Orlando, Florida, 32806, United States
Conditions
Explore the condition pages connected to this study.