Engineered t cells take on childhood brain cancers in new trial

NCT ID NCT04099797

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 36 times

Summary

This early-phase study tests a new gene therapy for people with aggressive brain tumors that have a protein called GD2. Researchers take a patient's own T cells, add a special receptor to help them recognize and attack GD2 on cancer cells, plus a gene that helps the T cells live longer. The goal is to find a safe dose and see if the cells can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.