ARTHROPATHY OF KNEE

This study looked at how to best use antibiotics to prevent infections in people having knee replacement surgery. About 1,770 adults were split into groups that got antibiotics either just before surgery or for a full day after. The goal was to see if a single dose works as well …

This study tested whether taking tamsulosin, a drug used for bladder problems, before hip or knee replacement surgery could prevent urinary retention (inability to pee) afterward. 170 men took either tamsulosin or a placebo for five days before and two days after surgery. The mai…

This completed trial looked at whether giving dexamethasone through a nerve block or through a vein works better for pain and inflammation after total knee replacement. 90 older adults were randomly assigned to one of two groups. Researchers measured how long pain relief lasted, …

This study looked at 90 adults having knee replacement surgery to see which nerve block technique works better for pain control and getting patients moving sooner. One group got a fascia iliaca plane block, the other got a combination of adductor canal and IPACK blocks. Researche…

This study compared robotic-assisted total knee replacement to the conventional technique in 95 patients with knee arthritis. The goal was to see if robotic surgery leads to better knee function, less pain, and higher satisfaction two years after the operation. Researchers also c…

This pilot study tested whether a weight loss program before total knee replacement helps improve recovery. 24 adults with obesity (BMI 35-40) were assigned to either a very low-calorie diet with health coaching or standard care. The goal was to see if the program was feasible an…

This completed study reviewed data from 31 patients who had knee replacement revision surgery due to aseptic loosening (the implant coming loose without infection). Researchers used a regional registry and X-ray analysis to understand the causes and economic impact. The goal was …

This study from the Mayo Clinic looked at 219 people getting total knee replacements to see if a blood test measuring an enzyme called tryptase could predict knee stiffness (arthrofibrosis) after surgery. Researchers measured tryptase levels before and after surgery and checked i…

This study looked at whether preserving or removing the infrapatellar fat pad (a small pad of fat in the knee) during total knee replacement leads to better outcomes for people with knee osteoarthritis. Over 370 participants were randomly assigned to one of two groups. Researcher…

This study looked at whether placing a drain in the knee after total knee replacement reduces early postoperative pain. Sixty patients over age 60 were randomly assigned to receive a drain or not. Pain was measured before surgery and at discharge using a 0-10 scale. The goal is t…