ARTHROPATHY OF KNEE
Clinical trials for ARTHROPATHY OF KNEE explained in plain language.
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Knee surgery infection prevention: one dose may be enough
Disease control CompletedThis study looked at the best way to give antibiotics before and after knee replacement surgery to prevent joint infections. About 1,770 adults having elective knee replacement took part. Researchers compared a single dose before surgery versus a longer 24-hour course to see whic…
Matched conditions: ARTHROPATHY OF KNEE
Phase: PHASE4 • Sponsor: Duke University • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Simple pill before joint surgery may prevent painful urinary blockage
Prevention CompletedThis study tested whether taking tamsulosin, a drug used for prostate problems, can prevent urinary retention after hip or knee replacement surgery. 170 men took the drug or a placebo for five days before and two days after surgery. The goal was to see if the drug reduced the nee…
Matched conditions: ARTHROPATHY OF KNEE
Phase: PHASE4 • Sponsor: Kantonsspital Graubünden • Aim: Prevention
Last updated May 17, 2026 10:42 UTC
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Robot or surgeon? knee replacement study reveals surprising results
Symptom relief CompletedThis study compared robotic-assisted knee replacement to the standard manual technique in 95 adults with knee arthritis. Researchers measured knee function, pain, and patient satisfaction over two years to see if the robotic approach leads to better outcomes without increasing co…
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: Hospital de Terrassa • Aim: Symptom relief
Last updated May 17, 2026 10:39 UTC
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Which nerve block gets knee patients moving faster?
Symptom relief CompletedThis study looked at 90 adults having knee replacement surgery to see which nerve block technique works better for pain and getting patients moving sooner. One group got a fascia iliaca block, the other got a combination of adductor canal and IPACK blocks. The main goal was to me…
Matched conditions: ARTHROPATHY OF KNEE
Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital • Aim: Symptom relief
Last updated May 17, 2026 10:39 UTC
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Knee surgery mystery: do drains actually help with pain?
Symptom relief CompletedThis study looked at whether placing a drain after knee replacement surgery helps reduce pain right after the operation. 60 patients over age 60 having a first-time knee replacement took part. Researchers measured pain before surgery and at discharge to see if drains made a diffe…
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: Hospital Universitario Reina Sofia de Cordoba • Aim: Symptom relief
Last updated May 17, 2026 10:38 UTC
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Weight loss before knee surgery shows promise in small trial
Symptom relief CompletedThis study tested whether a weight loss program before total knee replacement helps people with obesity have better outcomes. 24 adults aged 50-75 with a BMI between 35 and 40 followed a very low-calorie diet for 3 months before surgery and a maintenance diet for 3 months after. …
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Knee surgery showdown: to cut or keep the fat pad?
Symptom relief CompletedThis study looked at 377 people with knee osteoarthritis who needed total knee replacement. It compared what happens when surgeons remove a small fat pad at the front of the knee versus leaving it in place. The goal was to see which approach leads to better pain relief, daily fun…
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: Zhujiang Hospital • Aim: Symptom relief
Last updated Apr 26, 2026 20:03 UTC
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Blood enzyme may predict knee stiffness after replacement
Knowledge-focused CompletedThis study looked at whether a blood enzyme called tryptase can predict knee stiffness and pain after total knee replacement. Researchers measured tryptase levels before and after surgery in 219 adults with knee osteoarthritis. The goal was to see if these levels could help ident…
Matched conditions: ARTHROPATHY OF KNEE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC