AORTIC DISSECTION

This study tests a special tube called a stent graft to repair damage in the upper part of the main artery from the heart (the ascending aorta). It is for people with bulges (aneurysms), tears (dissections), or other lesions that usually need open-heart surgery. The goal is to se…

This study looks at two surgical approaches for repairing a tear in the aorta (the main artery from the heart) in 900 patients. One approach is less invasive (root-sparing), used for higher-risk patients, while the other is more extensive (root replacement and total arch repair),…

This study is testing a less invasive procedure using stent-grafts to treat various types of aortic disease, including aneurysms and dissections. It involves 170 participants who are considered too high-risk for traditional open surgery. The goal is to see if this endovascular ap…

This study is a registry that collects information on the AMDS stent, a device used to treat a life-threatening tear in the aorta (the main artery). The registry includes 301 adults aged 18-80 with acute DeBakey type I aortic dissection or intramural hematoma. The goal is to see …

This observational study follows 352 adults with aortic arch or descending aorta disease who receive the Thoraflex Hybrid device, sometimes with an additional RelayPro stent-graft. The goal is to evaluate safety and treatment success over 10 years, including risks like stroke, sp…

This study tests whether giving two drugs—Ulinastatin and Thymosin α1—right after emergency surgery for a torn aorta can prevent dangerous body-wide inflammation and organ failure. About 200 adults will receive the drugs, and doctors will track their organ function for a week. Th…

This study is a national registry in China that will track 500 women who experience an aortic dissection (a tear in the main artery) during pregnancy or within 12 weeks after giving birth. Researchers will collect information on treatments and outcomes for both mothers and babies…

This study follows 900 patients with a life-threatening tear in the aorta (type A aortic dissection) to compare outcomes between different surgical techniques. Researchers will track deaths, strokes, heart failure, and other complications within 30 days after surgery. The goal is…

This study is collecting information from 200 patients who had a type of aortic dissection (a tear in the main artery) and were treated with a procedure called STABILISE. The goal is to see how well the technique works and what complications may occur. Participants are adults wit…

This study involves 40 adults undergoing aortic arch surgery to repair aneurysms or dissections. Researchers are testing a new bedside system that measures brain chemicals in near real-time to detect early signs of oxygen deprivation. The goal is to prevent strokes and confusion …