Massive study aims to settle best surgery for deadly aortic tear

NCT ID NCT05912634

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Centre Cardiologique du Nord Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 900 patients with a life-threatening tear in the aorta (type A aortic dissection) to compare outcomes between different surgical techniques. Researchers will track deaths, strokes, heart failure, and other complications within 30 days after surgery. The goal is to understand which approach—repairing just the ascending aorta or also the aortic arch—offers the best balance of safety and long-term results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors choose the safest surgical method for aortic dissection, potentially reducing deaths and complications.
What could go wrong: This is an observational study, not a controlled trial, so results may not prove one surgery is better. Outcomes depend heavily on patient condition and surgeon skill.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aneurysm or dilatation of ascending aorta Aortic Dissection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC ARCH AORTIC DILATATION AORTIC DISSECTION AORTIC DISSECTION RUPTURE

Contacts and locations

Locations

Francesco Nappi

Saint-Denis, France, 93200, France

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