Can a drug combo save organs after aortic tear surgery?

NCT ID NCT06966687

ENROLLING_BY_INVITATION Disease control Sponsor: Nanjing Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving two drugs—Ulinastatin and Thymosin α1—right after emergency surgery for a torn aorta can prevent dangerous body-wide inflammation and organ failure. About 200 adults will receive the drugs, and doctors will track their organ function for a week. The goal is to reduce serious complications that often lead to death after this type of surgery.

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Conditions

The condition(s) this trial relates to.

aortic aneurysm Aortic Dissection Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC DISSECTION AORTIC DISSECTION ANEURYSM

Contacts and locations

Locations

Beijing Anzhen Hospital

Beijing, Beijing Municipality, China
Shanghai East Hospital Tongji University

Shanghai, Shanghai Municipality, China
The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China
West China Hospital

Chengdu, Sichuan, China

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