10-Year study tracks new device for aortic repair

NCT ID NCT05639400

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study follows 352 adults with aortic arch or descending aorta disease who receive the Thoraflex Hybrid device, sometimes with an additional RelayPro stent-graft. The goal is to evaluate safety and treatment success over 10 years, including risks like stroke, spinal cord injury, and death. Participants receive standard care and are monitored for complications and device performance.

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Conditions

The condition(s) this trial relates to.

aortic aneurysm Aortic Dissection Dissection, Thoracic Aorta thoracic aortic aneurysm Thoracic Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ascension St. Vincent Heart Center

    Indianapolis, Indiana, 46290, United States

  • Baylor College of Medicine - St. Luke's

    Houston, Texas, 77030, United States

  • CHU Nantes

    Saint-Herblain, France

  • CHU de Toulouse - Hôpital de Rangueil

    Toulouse, 31059, France

  • Cedars-Sinai Medical Centre

    Los Angeles, California, 90048, United States

  • Duke University Medical Centre

    Durham, North Carolina, 27710, United States

  • Hartford Hospital

    Hartford, Connecticut, 06106, United States

  • Hospital Clinic of Barcelona

    Barcelona, 08036, Spain

  • Keck Medical Centre of USC

    Los Angeles, California, 90089, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Medstar Washington Hospital Centre

    Washington D.C., District of Columbia, 20010, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Oxford University Hospitals NHS FT

    Oxford, OX3 9DU, United Kingdom

  • Paracelsus Medical University

    Salzburg, 5020, Austria

  • Policlinico Di S.Orsola, Universita' Di Bologna

    Bologna, 9 40138, Italy

  • Southampton General Hospital

    Southampton, SO16 6YD, United Kingdom

  • UPMC Presbyterian

    Pittsburgh, Pennsylvania, 15213, United States

  • UT Dell Medical / Ascension Texas Cardiovascular

    Austin, Texas, 78705, United States

  • University Hospitals Bristol and Weston NHS Foundation Trust

    Bristol, BS2 8HW, United Kingdom

  • University of Alabama in Birmingham Medical Center

    Birmingham, Alabama, 35294, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Freiburg

    Freiburg im Breisgau, Germany

  • University of Maryland

    Baltimore, Maryland, 21201, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • Washington University/Barnes Jewish Hospital

    St Louis, Missouri, 63110, United States

  • Weill Cornell medicine

    New York, New York, 10065, United States

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