AORTIC ANEURYSM

This study tests a new tool called the Rapidlink device, used during open surgery to repair or replace major blood vessels in the chest. About 150 adults needing aortic surgery will take part. The goal is to see if the device is safe and works well, with follow-up for two years a…

This study compares a new guidance system called LumiGuide to standard X-ray guidance during a complex type of aortic aneurysm repair (FEVAR). The goal is to see if LumiGuide can reduce the amount of X-ray time needed during the procedure. About 182 adults who need this surgery w…

This study looks at a special stent that doctors modify themselves to treat large aneurysms in the chest and belly area. The goal is to see if this less invasive approach is as safe and effective as traditional open surgery. About 80 people aged 50 and older with aneurysms that m…

This study tests a new device called the NEXUS stent graft to treat serious problems in the main artery near the heart, such as tears or bulges. About 110 adults will receive the stent through a small tube in a blood vessel, avoiding major open surgery. The goal is to see if the …

This study explores whether a portable device that measures chest vibrations (kinocardiography) can help diagnose aortic valve disease and thoracic aortic aneurysm. Researchers will compare these signals with standard imaging in 180 adults, including healthy controls. The goal is…

This study tests a 6-week program called Ready for Recovery that helps people prepare for aortic aneurysm repair. Ten adults having elective surgery will try the program to see if it is feasible and helpful. The goal is to improve readiness and recovery, not to cure the aneurysm.

This study looks at how the aorta behaves during exercise in people with aortic aneurysm. Researchers will use special MRI scans to measure artery flexibility and compare that to tissue samples from surgery. The goal is to help doctors and patients know what level of exercise is …

This study tests an AI software called Aorta AIM that automatically measures the aorta from CT scans. Researchers want to see if it is as accurate as expert doctors. About 250 adults who already had a chest or belly CT scan will take part. No extra scans or procedures are needed.…

This study is collecting health information from 5,000 people who have a genetic condition that can cause the aorta (the main artery from the heart) to weaken or tear. Researchers want to learn how different gene changes affect the disease and what other factors might make it bet…

This study looks at the strength and flexibility of the aorta (the main artery) in people with aortic disease who are having heart surgery. Researchers want to find out if certain patient traits are linked to a weaker aortic wall, which could raise the risk of a tear or rupture. …

This study aims to create a large collection of medical information, DNA, blood, and tissue samples from 15,000 people with and without heart conditions. Researchers will use this biobank to better understand diseases like aortic aneurysm, heart failure, and bicuspid aortic valve…

This study tests whether 3D printed models of a patient's own aortic aneurysm can help surgeons plan surgery better. Ten adults with thoracic or abdominal aortic aneurysms who are scheduled for non-emergency surgery will have their CT scans turned into physical models. The main g…