New stent system aims to tame dangerous aortic aneurysms

NCT ID NCT05636527

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks 70 people receiving the NEXUS aortic arch stent graft, a device placed inside the aorta to treat aneurysms (bulging weak spots). Researchers will monitor safety, device failures, and survival for up to 5 years. The goal is to see how well the stent works in routine medical practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
NEXUS aortic arch stent graft system (a device placed inside the aorta to reinforce a weakened area)
What this could lead to
If successful, this study could confirm that the NEXUS stent system is a safe and effective option for treating aortic arch aneurysms, potentially reducing the need for open-heart surgery.
What could go wrong
This is an observational study, not a randomized trial, so results may be less definitive. Risks include stroke, paralysis, kidney failure, or device failure, as noted in the outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP Henri Mondor

    RECRUITING

    Paris, France

    Contact

    Contact

  • Aretaieio Hospital

    RECRUITING

    Nicosia, Cyprus, 2024, Cyprus

    Contact

    Contact

  • Azienda Socio Sanitaria Territoriale (A.S.S.T.) degli Spedali Civili di Brescia

    NOT_YET_RECRUITING

    Brescia, 25123, Italy

    Contact

    Contact

  • Cliniques universitaires Saint Luc

    RECRUITING

    Brussels, 1200, Belgium

    Contact

    Contact

  • Evaggelismos General Hospital

    RECRUITING

    Athens, Greece

    Contact

    Contact

  • German Heart Center

    RECRUITING

    Berlin, Germany

    Contact

    Contact Email: •••••@•••••

  • Hospital Alvaro Cunqueiro Vigo

    RECRUITING

    Vigo, Galicia, 36312, Spain

    Contact

    Contact

    Contact

  • Hospital Universitario Puerta del Mar

    RECRUITING

    Cadiz, Andalusia, 11009, Spain

    Contact

    Contact

    Contact

  • Hôpital Européen Georges Pompidou

    RECRUITING

    Paris, France

    Contact

    Contact

  • Immanuel Klinikum Brandenburg, Herzzentrum Brandenburg

    RECRUITING

    Bernau bei Berlin, Brandenburg, 16321, Germany

    Contact

    Contact

  • Klinikum Hirslanden, Aorten -und Gefäßzentrum, Zuerich

    RECRUITING

    Zurich, Switzerland

    Contact

    Contact

  • Medical University of Warsaw

    RECRUITING

    Warsaw, Poland

    Contact

    Contact

  • Stichting Amsterdam UMC,

    RECRUITING

    Amsterdam, 1081, Netherlands

    Contact

    Contact

    Contact

  • UZ Leuven

    RECRUITING

    Leuven, 3000, Belgium

    Contact

    Contact

  • University Hospital Bonn

    RECRUITING

    Bonn, Germany

    Contact

    Contact

  • University Hospital Duesseldorf

    RECRUITING

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

    Contact

    Contact

    Contact

  • University Hospital Padoua

    RECRUITING

    Padova, Italy

    Contact

    Contact Email: •••••@•••••

    Contact

  • University Medical Center Groningen

    NOT_YET_RECRUITING

    Groningen, Netherlands

    Contact

    Contact

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