New stent graft could fix deadly aortic arch conditions

NCT ID NCT04471909

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new device called the NEXUS aortic arch stent graft system in 110 adults with serious conditions like aortic dissection or aneurysm affecting the aortic arch. The goal is to see if it is safe and effective at repairing the damaged area without major complications. Participants must meet specific size requirements for the stent placement areas.

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Conditions

The condition(s) this trial relates to.

aortic aneurysm Aortic Dissection Penetrating Atherosclerotic Ulcer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advent Health Orlando

    COMPLETED

    Orlando, Florida, 32804, United States

  • Ascension St. Vincent

    COMPLETED

    Carmel, Indiana, 46290, United States

  • Atrium Health

    RECRUITING

    Charlotte, North Carolina, 28203, United States

  • Auckland City Hospital

    RECRUITING

    Auckland, Grafton, 1023, New Zealand

  • Ballad Health

    COMPLETED

    Kingsport, Tennessee, 37660, United States

  • Baylor Scott and White

    RECRUITING

    Plano, Texas, 75093, United States

  • Carilion Clinic

    RECRUITING

    Roanoke, Virginia, 24014, United States

  • Duke University Medical Center

    COMPLETED

    Durham, North Carolina, 27710, United States

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06102, United States

  • Lankenau Medical Center

    COMPLETED

    Wynnewood, Pennsylvania, 19096, United States

  • MedStar Washington Hospital

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Northwell Health Lenox Hill Hospital

    RECRUITING

    New York, New York, 10075, United States

  • Oregon Health

    RECRUITING

    Portland, Oregon, 97239, United States

  • Sentara Norfolk General Hospital

    RECRUITING

    Norfolk, Virginia, 23507, United States

  • Stanford University School of Medicine

    RECRUITING

    Stanford, California, 94305, United States

  • The Lindner Research Center

    RECRUITING

    Cincinnati, Ohio, 45219, United States

  • The Mount Sinai Medical Center

    RECRUITING

    New York, New York, 10029, United States

  • The University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

  • Tufts Medical Center

    COMPLETED

    Boston, Massachusetts, 02111, United States

  • UC Davis Health

    COMPLETED

    Sacramento, California, 95817, United States

  • University Hospitals of Cleveland

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • University of Alabama Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

  • University of California San Diego Medical Center

    RECRUITING

    La Jolla, California, 92037, United States

  • University of Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Maryland

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

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