Custom stents could replace open surgery for deadly aortic bulges

NCT ID NCT06501872

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a doctor-modified stent-graft to treat large aneurysms in the chest and belly area. The goal is to see if this less invasive approach is as safe and effective as traditional open surgery. 80 people aged 50 and older with aneurysms meeting standard surgical size criteria will be enrolled. The main focus is survival at 30 days and freedom from major complications like stroke or kidney failure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Physician-modified aortic endograft (a stent-graft device)
What this could lead to
If this works, it could offer a less invasive treatment option for complex aortic aneurysms, potentially reducing recovery time and major complications compared to open surgery.
What could go wrong
This is a single-center study with only 80 participants, so results may not apply to everyone. The stent is modified by the doctor, which could lead to variability in outcomes. Risks include serious complications like stroke, paralysis, or organ failure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dartmouth-Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 03756, United States

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