ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

This study tests if a screw made from donated human bone works better than a standard plastic screw for ACL repair. About 80 people with a torn ACL will get one of the two screws during surgery. Researchers will use MRI and CT scans over two years to check if the bone tunnel wide…

This early-phase study tests whether a single injection of stem cells taken from the patient's own knee fat can safely improve healing and knee function after ACL reconstruction. Fifteen adults scheduled for ACL surgery will receive the stem cell injection during the procedure an…

This study tests whether tranexamic acid (TXA), a drug that reduces bleeding, can prevent arthritis after an ACL injury. 50 people aged 18-30 with a recent ACL tear will receive TXA to see if it lowers joint inflammation and protects cartilage. The goal is to stop post-traumatic …

This study compares two nerve block methods (AFCN block vs. adductor canal block) for pain control in children aged 8-18 having ACL or MPFL knee surgery. Researchers will measure pain levels, opioid use, and muscle strength recovery. The goal is to find which block provides bette…

This study tests whether a silk bandage or a medical glue works better to prevent skin problems like rashes and blisters after ACL knee surgery. About 100 people aged 14 to 60 having ACL reconstruction will be enrolled. The goal is to find which dressing causes fewer skin issues …

This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can speed up recovery after anterior cruciate ligament (ACL) knee reconstruction. About 40 adults aged 18-45 who need ACL surgery will receive either HBOT or standard care. The goa…

This study tests if a new tool called a dual-flow arthroscopy sheath can replace the traditional tourniquet during ACL knee surgery. The goal is to see if it leads to less pain and faster recovery. About 128 adults having their first ACL reconstruction will take part.

This study compares two surgical techniques for repairing a torn ACL, the main knee ligament. Forty adults with ACL injuries will be randomly assigned to one of two procedures. Researchers will measure knee stability, function, and re-tear rates over one year to see which method …

This study looks at how a single walking session with different visual cues affects movement and brain signals in 36 athletes who had ACL surgery. One type of cue is steady (isochronous), while the other has natural variations (fractal). The goal is to see if fractal cues can res…

This study looks at how using a special band to limit blood flow during exercise affects the body's immune cells and energy use in people recovering from ACL knee surgery. Researchers at Yale will study 20 adults to see how this training changes gene activity and chemical levels …