ANTERIOR CRUCIATE LIGAMENT INJURY
Clinical trials for ANTERIOR CRUCIATE LIGAMENT INJURY explained in plain language.
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New study tests extra support for repeat knee surgery
Disease control CompletedThis study looked at two ways to do revision ACL surgery—using an Achilles tendon graft alone or with an extra InternalBrace for support. Thirty-two people with a failed ACL graft were randomly assigned to one of the two procedures. Researchers measured knee function, symptoms, a…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: Medical University of Graz • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Knee surgery showdown: which graft gets athletes back in the game faster?
Disease control CompletedThis study looked at 65 professional athletes who had ACL reconstruction surgery using either a bone-patellar tendon-bone graft or a hamstring tendon graft. Researchers measured muscle strength, knee function, and how quickly athletes returned to their sport, following them for u…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Knee surgery showdown: stitch or rebuild for torn ACL?
Disease control CompletedThis study tested if stitching a torn anterior cruciate ligament (ACL) back together and adding a special support is as good as the standard reconstruction using a hamstring tendon. 48 active adults aged 18-30 with a first-time ACL tear took part. The main goal was to see how wel…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: Orthopedisch Centrum Oost Nederland • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Shocking ACL recovery: electric pulses and eccentric lifts show promise
Disease control CompletedThis study tested whether adding neuromuscular electrical stimulation (NMES) and eccentric leg press exercises to standard rehabilitation can help people regain muscle strength and protect knee cartilage after anterior cruciate ligament (ACL) reconstruction. 135 participants who …
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Athletes' own blood may speed knee healing after ACL surgery
Disease control CompletedThis study tested whether applying platelet-rich fibrin (PRF), a gel made from the patient's own blood, to the knee after ACL reconstruction can reduce numbness and improve function. Fifty-three male athletes were split into two groups: one received PRF during surgery, the other …
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Sponsor: University of Belgrade • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New study tests simpler ACL graft to preserve leg strength
Disease control CompletedThis trial compared two types of hamstring tendon grafts for repairing a torn anterior cruciate ligament (ACL) in the knee. 42 patients received either a graft using only the semitendinosus tendon or a graft using both the semitendinosus and gracilis tendons. The main goal was to…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: Fundacion Clinica Valle del Lili • Aim: Disease control
Last updated Jun 26, 2026 18:48 UTC
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Pre-Surgery workouts boost knee recovery after ACL repair
Symptom relief CompletedThis study looked at whether doing a structured exercise program for six weeks before ACL knee surgery helps people recover faster and better. 76 adults with a torn ACL were split into two groups: one did pre-surgery exercises (prehabilitation), and the other had standard care. R…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: Beni-Suef University • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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New study tests pain relief without opioids after ACL surgery
Symptom relief CompletedThis study looked at whether a nonopioid pain regimen works as well as standard opioids after anterior cruciate ligament (ACL) reconstruction. 90 adults having ACL surgery were randomly assigned to receive either nonopioid or opioid pain control. The goal was to see if the nonopi…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: PHASE2, PHASE3 • Sponsor: Henry Ford Health System • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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PRP boost for ACL surgery? small study tests knee recovery
Symptom relief CompletedThis study compared knee function after ACL reconstruction using a hamstring graft, with or without adding platelet-rich plasma (PRP). Sixty patients aged 18-40 with ACL injuries were enrolled. The goal was to see if PRP improves outcomes like knee stability and function.
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: Muhammad Aamir Latif • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Mind over muscle: mental training boosts ACL recovery
Symptom relief CompletedThis study looked at whether a type of mental coaching, called operant conditioning, could help improve thigh muscle strength and activation in people who had ACL surgery. Eleven adults aged 18-45 who had ACL reconstruction took part. The goal was to see if this brain-training ap…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Leg injuries throw off balance, study finds
Knowledge-focused CompletedThis study looked at how muscle strength and balance differ between healthy people and those with chronic ankle instability or ACL knee injuries. Researchers measured balance using a special platform. The goal was to better understand the link between strength and stability after…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Sponsor: Biruni University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Hidden weakness after ACL surgery revealed by jump test
Knowledge-focused CompletedThis study looked at how people produce force during a vertical jump about six months after anterior cruciate ligament (ACL) reconstruction. Researchers compared 100 participants — some who had ACL surgery and some healthy — to see if strength differences between legs persist eve…
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Sponsor: Haute Ecole ARC Sante • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Knee surgery showdown: stitch the stump or snip it?
Knowledge-focused CompletedThis study compared two ways to repair a torn anterior cruciate ligament (ACL): one where surgeons stitch the torn ligament stump around the new graft, and the standard method where the stump is removed. 190 patients with recent ACL tears were randomly assigned to one of the two …
Matched conditions: ANTERIOR CRUCIATE LIGAMENT INJURY
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC