Extra nerve block may ease pain after ACL repair
NCT ID NCT07683078
First seen Jul 06, 2026 · Last updated Jul 15, 2026 · Updated 3 times
Summary
This study tests whether adding a nerve block to the vastus medialis muscle improves pain control after anterior cruciate ligament (ACL) reconstruction surgery. Participants receive either a standard adductor canal block alone or combined with the extra nerve block before surgery. Pain levels, opioid use, and recovery times are compared over the first 24 hours. The goal is to see if the combination provides better pain relief without delaying movement.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If successful, this could offer a better way to manage pain after ACL surgery, potentially reducing opioid use and speeding up recovery.
- What could go wrong
- This is a small, early-stage trial, so results may not apply to all patients. Adding an extra nerve block carries a small risk of complications like nerve injury or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
104 people
The number who actually took part.
- Started
-
Mar 2026
- Finished
-
Jul 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 65 years. * Scheduled for elective primary arthroscopic anterior cruciate ligament (ACL) reconstruction. * American Society of Anesthesiologists (ASA) physical status I or II. * Ability to provide written informed consent. Exclusion Criteria: * Previous surgery on the ipsilateral knee. * Bilateral knee surgery. * Coagulopathy or ongoing anticoagulant therapy contraindicating regional anesthesia. * Peripheral neuropathy or neuromuscular disease. * Local infection at the block injection site. * Known allergy or hypersensitivity to amide local anesthetics. * Contraindication to regional anesthesia. * Refusal to participate in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
SBU Bagcilar Education and Training Hospital
Istanbul, ABD Dışında, 34400, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Phone-Based prehab may boost ACL recovery