Extra nerve block may ease pain after ACL repair

NCT ID NCT07683078

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 06, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This study tests whether adding a nerve block to the vastus medialis muscle improves pain control after anterior cruciate ligament (ACL) reconstruction surgery. Participants receive either a standard adductor canal block alone or combined with the extra nerve block before surgery. Pain levels, opioid use, and recovery times are compared over the first 24 hours. The goal is to see if the combination provides better pain relief without delaying movement.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If successful, this could offer a better way to manage pain after ACL surgery, potentially reducing opioid use and speeding up recovery.
What could go wrong
This is a small, early-stage trial, so results may not apply to all patients. Adding an extra nerve block carries a small risk of complications like nerve injury or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

104 people

The number who actually took part.

Started

Mar 2026

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years. * Scheduled for elective primary arthroscopic anterior cruciate ligament (ACL) reconstruction. * American Society of Anesthesiologists (ASA) physical status I or II. * Ability to provide written informed consent. Exclusion Criteria: * Previous surgery on the ipsilateral knee. * Bilateral knee surgery. * Coagulopathy or ongoing anticoagulant therapy contraindicating regional anesthesia. * Peripheral neuropathy or neuromuscular disease. * Local infection at the block injection site. * Known allergy or hypersensitivity to amide local anesthetics. * Contraindication to regional anesthesia. * Refusal to participate in the study.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • SBU Bagcilar Education and Training Hospital

    Istanbul, ABD Dışında, 34400, Turkey (Türkiye)

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