Athletes' own blood may speed knee healing after ACL surgery
NCT ID NCT07257666
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether applying platelet-rich fibrin (PRF), a gel made from the patient's own blood, to the knee after ACL reconstruction can reduce numbness and improve function. Fifty-three male athletes were split into two groups: one received PRF during surgery, the other standard closure. The main goal was to see if PRF reduced sensory loss at the donor site one year after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- platelet-rich fibrin (PRF)
- What this could lead to
- If it works, this could point toward a simple way to improve recovery and reduce numbness after ACL surgery.
- What could go wrong
- This is a small, early pilot study with only 53 participants, so results may not apply to everyone. PRF is made from the patient's own blood, so risks are low but benefits are still unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANTERIOR CRUCIATE LIGAMENT INJURY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Clinical Center of Serbia (UKCS)
Belgrade, 11000, Serbia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can the ankle fully recover after donating a tendon for ACL repair?
- Muscle biofeedback may speed knee recovery — a trial puts it to the test
- Mind over knee: can psychological readiness predict a safe return to sport after ACL surgery?
- Which tendon graft helps female athletes recover best after ACL surgery?
- Knee surgery showdown: button vs. screw for ACL graft fixation
- Light exercise with a blood pressure cuff may rebuild leg muscle after knee replacement