ANESTHESIA, LOCAL
Clinical trials for ANESTHESIA, LOCAL explained in plain language.
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Nerve block may boost brain blood flow after stroke
Disease control ENROLLING_BY_INVITATIONThis study tests whether a nerve block in the neck can increase blood flow to the brain in people who develop narrowed blood vessels after a bleeding stroke. Ten adults in the ICU will receive the block, and researchers will measure changes in blood flow and neurological function…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Skin cancer surgery pain showdown: four numbing drugs compared in major trial
Symptom relief ENROLLING_BY_INVITATIONThis study tests four different numbing medicines (lidocaine, bupivacaine, chlorprocaine, and mepivacaine) to see which one causes the least pain when re-injected during Mohs skin cancer surgery. About 400 adults having Mohs surgery will rate their pain on a 1-10 scale. The goal …
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE4 • Sponsor: Baylor Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Can a simple fat infusion wake up numb skin faster?
Symptom relief OngoingThis study tests whether an intravenous fat emulsion called Intralipid 20% can reverse the numbing effect of common local anesthetics like lidocaine and bupivacaine. Eighteen healthy volunteers receive small injections of these anesthetics in their thigh, followed by either Intra…
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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New spinal anesthesia method could speed up recovery after joint replacement
Knowledge-focused OngoingThis study looks at using a smaller dose of a lighter-than-normal numbing medicine (hypobaric bupivacaine) injected into the lowest space in the spine for hip or knee replacement surgery. The goal is to see if this approach still works well for pain control during surgery while h…
Matched conditions: ANESTHESIA, LOCAL
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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EDS Patients' numbing shots put to the test
Knowledge-focused OngoingThis study compares how people with Ehlers-Danlos syndrome (EDS) and healthy volunteers respond to local anesthetics like lidocaine and bupivacaine. Researchers inject a small amount under the skin and measure pain sensation at different times. The goal is to find out if reported…
Matched conditions: ANESTHESIA, LOCAL
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC