ANESTHESIA, LOCAL
Clinical trials for ANESTHESIA, LOCAL explained in plain language.
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Eye ultrasound may spot spinal headaches early
Diagnosis CompletedThis study looked at whether measuring the optic nerve sheath with ultrasound can help predict postdural puncture headache (PDPH) in 176 adults having knee replacement under spinal anesthesia. PDPH is a headache that gets worse when sitting or standing and better when lying down.…
Matched conditions: ANESTHESIA, LOCAL
Sponsor: Ankara City Hospital Bilkent • Aim: Diagnosis
Last updated May 17, 2026 04:30 UTC
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Nerve block may cut opioid use after heart surgery
Symptom relief CompletedThis study tested a nerve block (a numbing injection) to see if it could reduce the need for strong painkillers after open-heart surgery. 340 adults having heart surgery through a chest cut (median sternotomy) took part. Half got the nerve block with a numbing medicine, the other…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: Unity Health Toronto • Aim: Symptom relief
Last updated May 17, 2026 04:18 UTC
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New pain block beats standard shot for gallbladder surgery recovery
Symptom relief CompletedThis study tested different ways to manage pain after keyhole gallbladder removal in 160 adults. Some patients received a nerve block (TAP block), local anesthetic, both, or no extra pain relief. The TAP block group reported less pain and fewer wound problems in the first 24 hour…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: University of Warmia and Mazury in Olsztyn • Aim: Symptom relief
Last updated May 17, 2026 04:12 UTC
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New pain block technique matches standard for heart surgery recovery
Symptom relief CompletedThis study tested two ways to numb the chest after a type of heart surgery. One method (ESPB) was compared to the standard method (PVB) to see if it worked just as well for pain control. 140 adults having minimally invasive heart bypass surgery took part. The goal was to find whi…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: Peking University Third Hospital • Aim: Symptom relief
Last updated May 17, 2026 04:12 UTC
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Numbing cream showdown: which one hurts less?
Symptom relief CompletedThis study tested two different numbing creams on 22 adults getting laser treatment for sun-damaged skin. Each person tried both creams on different sides of their face to see which one reduced pain more. The goal was to find the best way to make the laser procedure more comforta…
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE2, PHASE3 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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New anesthesia combo may ease Post-Surgery pain for hand operations
Symptom relief CompletedThis study tested two ways of numbing the arm for hand, wrist, or elbow surgery to see which one reduces pain after the procedure. 91 adults having outpatient surgery received either lidocaine alone or lidocaine plus ropivacaine. The goal was to find which approach gives better p…
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE1 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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New catheter approach may ease hand surgery pain better
Symptom relief CompletedThis study tested two methods of placing a tiny tube (catheter) near nerves to deliver pain medicine after hand surgery. 140 adults having hand surgery took part. The goal was to see which method provides better numbness and pain relief, helping patients recover more comfortably …
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Which nerve block wins for post-surgery pain? new study has answers.
Symptom relief CompletedThis study tested three different numbing methods to reduce pain after chest surgery (thoracoscopy). 155 adults were randomly assigned to receive a serratus plane block, a paravertebral block, or both together before surgery. The goal was to see which method works best for contro…
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated May 06, 2026 16:13 UTC
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Breathing easy: new inhaler may ease pain during male scrotal procedures
Symptom relief CompletedThis study tested whether inhaling a pain-relief medicine called Penthrox (methoxyflurane) can help men feel less pain and anxiety during minor scrotal surgeries done with local anesthetic. Forty adult patients were randomly assigned to receive either local anesthetic alone or lo…
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE2 • Sponsor: University of Manitoba • Aim: Symptom relief
Last updated May 06, 2026 16:03 UTC
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Eye gel may block infection prevention before surgery
Knowledge-focused CompletedThis study looked at whether a numbing eye gel (chloroprocaine 3%) creates a barrier that stops povidone-iodine, a germ-killing solution used before eye surgery, from working properly. 100 adults had bacteria swabs taken from their eyes before and after the gel and germ-killer we…
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE4 • Sponsor: Harrow Inc • Aim: Knowledge-focused
Last updated May 14, 2026 12:01 UTC