ANESTHESIA, LOCAL
Clinical trials for ANESTHESIA, LOCAL explained in plain language.
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New anesthesia method may cut opioid use after back surgery
Symptom relief Recruiting nowThis study tests whether a specific injection technique called erector spinae plane block (ESPB) reduces pain and opioid use after lumbar spinal fusion better than standard subcutaneous anesthesia. Researchers will enroll 66 adults scheduled for one- or two-level lumbar fusion. P…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Skip the fast? study tests if eating before surgery eases anxiety
Symptom relief Recruiting nowThis study looks at whether eating solid food before a WALANT procedure (a type of hand surgery using only local anesthesia) can reduce anxiety and nausea compared to fasting. Researchers will randomly assign 134 participants to either eat or fast before their surgery and then co…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: University of California, Irvine • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Silver solution may ease pain at the dentist for children with MIH
Symptom relief Recruiting nowThis study tests if applying silver diamine fluoride (SDF) to children's molars affected by molar incisor hypomineralization (MIH) helps local anesthesia work better during fillings. Fifty children will receive either SDF or a placebo before dental work. The goal is to see if SDF…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Knee replacement pain study seeks best steroid dose
Symptom relief Recruiting nowThis study looks at using different amounts of steroids injected into the knee during total knee replacement surgery to control pain. Researchers want to find the safest and most effective dose to help patients recover faster and feel better. The trial involves 120 adults having …
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: First Affiliated Hospital of Fujian Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Small study seeks best numbing dose for skin surgery
Knowledge-focused Recruiting nowThis study is testing how long two different volumes of a common numbing medicine (lidocaine with epinephrine) keep the skin numb during dermatologic surgery. Researchers will inject either 0.5 ml or 1.0 ml into the side of the nose in 35 adults and check every 15 minutes when fe…
Matched conditions: ANESTHESIA, LOCAL
Phase: PHASE4 • Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Could local anesthesia be better for older hernia patients? a new study investigates.
Knowledge-focused Recruiting nowThis pilot study is testing whether local anesthesia (with sedation) works as well as general anesthesia for inguinal hernia repair in veterans aged 60 and older. The goal is to gather data to plan a larger, more definitive trial. About 80 participants will be followed for 6 mont…
Matched conditions: ANESTHESIA, LOCAL
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC