ANAL CANCER
Clinical trials for ANAL CANCER explained in plain language.
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New Triple-Drug attack aims to shrink Hard-to-Treat cancers
Disease control OngoingThis study tests a combination of three drugs (entinostat, PDS01ADC, and bintrafusp alfa) in adults with advanced cancers linked to HPV or certain colon cancers that haven't responded well to standard treatments. The goal is to find a safe dose and see if the combo can shrink tum…
Matched conditions: ANAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 16, 2026 23:49 UTC
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New drug combo shows promise for tough cancers
Disease control OngoingThis early-stage study tests a new drug called KFA115, alone or with pembrolizumab, in people with advanced cancers like lung, skin, kidney, and others. The main goal is to find the safest dose and understand side effects. About 126 participants will be enrolled to see if the tre…
Matched conditions: ANAL CANCER
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 16, 2026 23:49 UTC
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New hope for advanced cancers: immunotherapy drug shows promise in large trial
Disease control OngoingThis study tested the drug pembrolizumab in over 1,600 people with various advanced solid tumors that had stopped responding to standard treatments. The goal was to see if the drug could shrink or control the tumors. The trial focused on identifying which patients were most likel…
Matched conditions: ANAL CANCER
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New drug cocktail shows promise against Hard-to-Treat HPV cancers
Disease control OngoingThis study tests whether a mix of three immunotherapy drugs can shrink tumors in people with advanced HPV-related cancers that have spread or not responded to standard treatments. About 51 adults with cancers like cervical, anal, or throat cancer will receive the drugs for up to …
Matched conditions: ANAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New HPV vaccine combo shows promise against tough cancers
Disease control OngoingThis study tests an HPV vaccine (PRGN-2009) alone or combined with a drug called M7824 in adults with HPV-positive cancers like cervical, anal, and throat cancers. The goal is to find a safe dose and see if the combination boosts the immune system's attack on tumors. Participants…
Matched conditions: ANAL CANCER
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:37 UTC
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New dual-immunotherapy combo tested in advanced cancers
Disease control OngoingThis early-phase study tests a new drug, AI-061, which combines two immunotherapy agents (anti-PD-1 and anti-CTLA-4) into one treatment for people with advanced solid tumors that have stopped responding to standard therapies. The main goal is to find the safest dose and check for…
Matched conditions: ANAL CANCER
Phase: PHASE1 • Sponsor: OncoC4, Inc. • Aim: Disease control
Last updated May 08, 2026 12:01 UTC
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Could less radiation be better for anal cancer patients?
Symptom relief OngoingThis study is for people with locally advanced anal cancer. It tests whether giving a lower dose of radiation to nearby lymph nodes can reduce side effects like diarrhea and skin problems, compared to the standard dose. About 33 participants will receive chemoradiation with the r…
Matched conditions: ANAL CANCER
Phase: PHASE2, PHASE3 • Sponsor: University of Cincinnati • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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New program aims to slash cancer wait times in botswana communities
Knowledge-focused OngoingThis study tests a program called Potlako+ that combines community education, help for healthcare workers, and patient guides to speed up cancer detection and treatment. About 874 adults in Botswana with cancer symptoms or at risk will take part. Half the communities get the prog…
Matched conditions: ANAL CANCER
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC