ALZHEIMERS DISEASE

This Phase 3 trial tests whether trontinemab can slow down Alzheimer's in people with early symptoms like mild memory problems. About 800 volunteers will receive either the drug or a placebo by IV for 72 weeks. The study measures changes in thinking, daily function, and safety.

This Phase 3 trial tests trontinemab, an antibody given by IV, in 800 people with early Alzheimer's (mild cognitive impairment to mild dementia). Half get the drug, half get a placebo, for 72 weeks. The goal is to see if it slows decline in memory, thinking, and daily activities.

This study tests a surgical procedure called deep cervical lymphatic venous anastomosis (DC-LVA) in 376 people with moderate-to-severe Alzheimer's disease. The surgery connects lymph vessels in the neck to veins, aiming to improve drainage of waste from the brain. Researchers wil…

This study tests a nasal spray called foralumab in 16 people with early Alzheimer's or mild cognitive impairment. The spray aims to reduce brain inflammation by calming overactive immune cells. Participants will use the spray three times a week for eight weeks and have brain scan…

This study tests whether the drug remternetug can prevent or slow the buildup of harmful proteins in the brains of people who have a genetic mutation that almost always causes early-onset Alzheimer's. About 280 participants will receive either the drug or a placebo every 12 weeks…

This study tests a drug called remternetug in people who have a strong genetic risk for Alzheimer's but do not yet have symptoms. The goal is to see if the drug can prevent or slow the buildup of harmful proteins in the brain. About 280 participants will receive either the drug o…

This study is a large-scale screening program to find people who may be eligible for Roche's Alzheimer's drug trials. It involves a simple blood test and a memory assessment. Up to 13,000 participants with memory concerns will be evaluated. No experimental treatment is given in t…

This study looks at how people with mild cognitive impairment (MCI) and Alzheimer's disease adjust their walking when conditions change, like walking on different surfaces. Researchers will measure walking patterns, memory, and thinking skills in 10 older adults. The goal is to b…

This study aims to scientifically prove that music therapy affects the brain in people with Alzheimer's disease. Researchers will measure brain-related molecules (like serotonin and dopamine) in saliva before and after music sessions. The study includes 60 adults: 20 with Alzheim…