Nasal spray could tame brain inflammation in early Alzheimer's

NCT ID NCT06489548

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a nasal spray called foralumab in 16 people with early Alzheimer's or mild cognitive impairment. The spray aims to reduce brain inflammation by calming overactive immune cells. Participants will use the spray three times a week for eight weeks and have brain scans, memory tests, and blood draws over six months to check safety and effects.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Alzheimer Research and Treatment, Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

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