Could this pill stop Alzheimer's before it starts? new trial targets High-Risk gene carriers
NCT ID NCT07399171
First seen Feb 12, 2026 · Last updated May 15, 2026 · Updated 9 times
Summary
This study tests an experimental drug, HT-4253, to see if it can lower the risk of developing Alzheimer's disease in people who carry the APOE4 gene and have early signs of brain changes. About 112 participants aged 50-75 will receive either the drug or a placebo for 48 weeks. The goal is to move participants from a high-risk to a low-risk score on a blood test that measures Alzheimer's-related proteins.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic Abu Dhabi
Abu Dhabi, United Arab Emirates
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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