Could a diabetes drug calm brain inflammation in Alzheimer's?
NCT ID NCT05891496
First seen Feb 26, 2026 · Last updated May 15, 2026 · Updated 14 times
Summary
This study tested whether semaglutide, a medicine used for diabetes and weight loss, can reduce inflammation in the brain and body of people with early Alzheimer's disease. 23 participants received either semaglutide or a placebo for 12 weeks, then everyone received semaglutide for another 52 weeks. The goal was to see if the drug changes immune system activity and is safe for Alzheimer's patients.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Azienda Ospedaliera Spedali Civili di Brescia
Brescia, 25123, Italy
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Azienda Ospedaliera di Perugia;Ospedale S. Maria della Miser
Perugia, 06132, Italy
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Banner Sun Health Research Institute
Sun City, Arizona, 85351, United States
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Brain Matters Research
Delray Beach, Florida, 33445, United States
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Centre de la Mémoire
Geneva, 1205, Switzerland
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Fondazione Santa Lucia IRCCS
Roma, 00179, Italy
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Karolinska Universitetssjukhuset, Huddinge
Stockholm, 141 86, Sweden
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Memory Program
Toronto, Ontario, M3B2S7, Canada
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Ottawa Memory Clinic
Ottawa, Ontario, K1Z 1G3, Canada
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Rigshospitalet - afsnit 8015
København Ø, 2100, Denmark
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Rigshospitalet - afsnit 8015 Hukommelsesklinikken
København Ø, 2100, Denmark
Conditions
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