Could a diabetes drug tame Alzheimer's inflammation?
NCT ID NCT05891496
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether semaglutide, a medicine used for diabetes and weight loss, can reduce inflammation in the brain and body of people with early Alzheimer's disease. Twenty-three participants with mild memory problems or mild dementia received either semaglutide or a placebo for 12 weeks, then all received semaglutide for another 52 weeks. The goal was to see how the drug affects immune system activity, not to cure the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Azienda Ospedaliera Spedali Civili di Brescia
Brescia, 25123, Italy
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Azienda Ospedaliera di Perugia;Ospedale S. Maria della Miser
Perugia, 06132, Italy
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Banner Sun Health Research Institute
Sun City, Arizona, 85351, United States
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Brain Matters Research
Delray Beach, Florida, 33445, United States
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Centre de la Mémoire
Geneva, 1205, Switzerland
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Fondazione Santa Lucia IRCCS
Roma, 00179, Italy
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Karolinska Universitetssjukhuset, Huddinge
Stockholm, 141 86, Sweden
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Memory Program
Toronto, Ontario, M3B2S7, Canada
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Ottawa Memory Clinic
Ottawa, Ontario, K1Z 1G3, Canada
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Rigshospitalet - afsnit 8015
København Ø, 2100, Denmark
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Rigshospitalet - afsnit 8015 Hukommelsesklinikken
København Ø, 2100, Denmark