ALOPECIA AREATA

This study tested whether low doses of IL2, a protein that helps regulate the immune system, could treat severe alopecia areata (patchy hair loss). 44 adults with at least 50% scalp hair loss that did not respond to standard treatments received either IL2 or a placebo. The goal w…

This study tested a pill called baricitinib in 606 adults with severe or very severe alopecia areata, a condition causing major hair loss. The goal was to see if it could safely regrow scalp hair compared to a placebo. Results showed that baricitinib helped many participants achi…

This study looked at the long-term safety and effectiveness of an experimental drug (PF-06651600) for adults and teens aged 12 and older with alopecia areata, a condition that causes patchy or total hair loss. Over 1,000 participants received the drug for up to several years, and…

This study looked at the long-term safety and effectiveness of the drug CTP-543 in adults with moderate to severe alopecia areata, a condition that causes patchy hair loss. Over 400 participants who had already completed a previous CTP-543 trial took the drug for up to 108 weeks.…

This study tested whether tofacitinib, a drug already approved for other conditions, is safe and helpful for people with Down syndrome who also have immune-related skin problems like eczema, psoriasis, or hair loss. The study included 47 adolescents and adults. Researchers measur…

This study tested two doses of baricitinib, a pill, in 784 adults with severe or very severe alopecia areata, a condition causing patchy or total hair loss. The goal was to see if the drug could regrow scalp hair better than a placebo. Participants took the drug daily, and doctor…

This study tested an oral medication called roflumilast against steroid injections for people with mild to moderate patchy alopecia areata. Fifty adults took part to see which treatment better helps hair regrow over 16 weeks. The goal is to find a simpler, pill-based option for t…

This study tested a light-based device called Lumiton to see if it could improve skin and hair conditions like psoriasis, alopecia areata, and polymorphous light eruption. Eighteen adults used the device at home, and researchers measured changes in disease severity using photos a…

This study examined whether a specific change in the TLR7 gene (rs3853839) is more common in people with alopecia areata, an autoimmune condition that causes hair loss. Researchers compared 120 participants—those with alopecia areata and healthy volunteers—to see if the gene vari…