ALOPECIA AREATA

This early-stage trial is testing an experimental oral medication called VC005 in adolescents aged 12 to 18 with severe alopecia areata, a condition that causes patchy or complete hair loss. The study aims to understand how the drug is processed by the body, whether it is safe, a…

This trial is testing an experimental oral medication, VC005, in adults with severe alopecia areata—an autoimmune condition that causes patchy or complete hair loss. Participants will take either VC005 or a placebo daily for 24 weeks. The main goal is to see if the drug can reduc…

This phase 3 trial tests whether the experimental drug ritlecitinib can safely and effectively regrow hair in people aged 12 and older with moderate alopecia areata, a condition causing patchy hair loss. Participants take a daily capsule for 24 weeks, with some receiving placebo.…

This trial investigates whether fecal microbiota transplantation (FMT) can treat alopecia areata, an autoimmune condition causing patchy hair loss. Researchers will give adults with alopecia areata either FMT or a placebo for three days and track hair regrowth, immune changes, an…

This trial tests whether a custom cream containing metformin (a diabetes drug), simvastatin (a cholesterol drug), and betamethasone (a steroid) can regrow hair in people with patchy alopecia areata, an autoimmune condition causing hair loss. Participants apply the cream twice dai…

This study tests whether a gel containing methotrexate, an immune-suppressing drug, can regrow hair in people with localized alopecia areata better than minoxidil spray. About 268 adults with less than 25% scalp hair loss will apply one of the two treatments twice daily for 24 we…

This study tests whether a vitamin D-based cream (calcipotriol) works as well as steroid injections for regrowing hair in people with patchy alopecia areata. Sixty adults with less than half their scalp affected will use one of the two treatments for 12 weeks. The goal is to see …

This study compares two oral medications—tofacitinib and methotrexate—for treating severe alopecia areata, an autoimmune condition causing hair loss. 78 adults aged 18-60 with severe scalp or total body hair loss will take one of the drugs for 12 weeks. The main goal is to see wh…

This study measures how often depression occurs in adults with alopecia areata, a condition that causes patchy hair loss. Researchers will use a questionnaire to assess depressive symptoms in 100 patients at a dermatology clinic. No treatments or interventions are involved — the …

This study will collect existing medical records from about 20,000 people aged 12 and older in Italy who have one of five inflammatory skin conditions: psoriasis, atopic dermatitis, vitiligo, alopecia areata, or hidradenitis suppurativa. Researchers want to describe who gets thes…