ADVANCED BREAST CANCER
Clinical trials for ADVANCED BREAST CANCER explained in plain language.
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New cancer drug injected directly into tumors shows promise in early trial
Disease control CompletedThis early-stage study tested a new drug, CyPep-1, which is injected directly into tumors. It was combined with the immunotherapy drug pembrolizumab to see if it could help control advanced head and neck cancer, melanoma, or triple-negative breast cancer. The main goals were to c…
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Cytovation AS • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New Triple-Threat treatment tested for tough breast cancers
Disease control CompletedThis study tested whether combining three medications—olaparib, palbociclib, and fulvestrant—is safe for people with advanced breast cancer that is hormone-sensitive and has a BRCA gene mutation. The main goal was to check for side effects and see how long patients lived without …
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Safety check for advanced breast cancer combo in indian patients
Disease control CompletedThis study checked the safety of a two-drug combination (alpelisib and fulvestrant) for people in India with advanced breast cancer that has a specific genetic change (PIK3CA mutation) and has worsened after hormone therapy. It involved 40 men and post-menopausal women. The main …
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE4 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Cancer patients try virtual rehab: does it work as well as In-Person?
Symptom relief CompletedThis study tested whether group-based cancer rehabilitation works better when delivered virtually or in-person for people with advanced breast or colorectal cancer. Researchers enrolled 111 participants to compare how well patients stick with each format and which they prefer. Th…
Matched conditions: ADVANCED BREAST CANCER
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Can your medical records replace a clinical trial?
Knowledge-focused CompletedThis study aimed to see if information from real-world electronic health records can reliably answer cancer treatment questions. Researchers recreated a past breast cancer drug trial using data from nearly 4,000 patients' medical records instead of running a new trial. The goal w…
Matched conditions: ADVANCED BREAST CANCER
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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First look: how a breast cancer drug behaves in chinese patients
Knowledge-focused CompletedThis study aimed to understand how the breast cancer drug palbociclib is absorbed and processed in the body of Chinese patients. It involved 26 postmenopausal Chinese women with a specific type of advanced breast cancer. The main goal was to measure drug levels in the blood after…
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Can your medical records replace a clinical trial?
Knowledge-focused CompletedThis study did not test a new treatment. Instead, researchers used existing electronic health records from over 2,400 women with advanced breast cancer to see if this real-world data can reliably answer the same questions as a traditional, expensive clinical trial. The goal is to…
Matched conditions: ADVANCED BREAST CANCER
Sponsor: Shirley Vichy Wang • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:15 UTC