ADVANCED BREAST CANCER
Clinical trials for ADVANCED BREAST CANCER explained in plain language.
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New drug cocktail shows promise for BRCA breast cancer patients
Disease control CompletedThis early-phase trial tested a combination of three drugs (olaparib, palbociclib, and fulvestrant) in 9 adults with BRCA-mutated, hormone receptor-positive, HER2-negative breast cancer that had spread or could not be removed. The main goal was to see if the combination was safe …
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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New daily pill shows promise in early breast cancer trial
Disease control CompletedThis early-phase study tested a new daily pill called TQB3616 in 40 adults with advanced breast cancer that had stopped responding to standard hormone therapy. The pill works by blocking certain proteins that help cancer cells multiply. The main goals were to find a safe dose and…
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE1 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Experimental shot targets tumors in Late-Stage cancers
Disease control CompletedThis early-phase trial tested a new drug called CyPep-1, injected directly into tumors, combined with the immunotherapy pembrolizumab. It included 6 adults with advanced head and neck, melanoma, or triple-negative breast cancer that had spread. The goal was to see if the combinat…
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE1, PHASE2 • Sponsor: Cytovation AS • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New drug combo shows safety promise for tough breast cancer
Disease control CompletedThis study tested the safety of two drugs, alpelisib and fulvestrant, in 40 men and postmenopausal women with a specific type of advanced breast cancer (HR+, HER2-, with a PIK3CA mutation) that had worsened after hormone therapy. The goal was to see how many people had side effec…
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE4 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Can virtual rehab help advanced cancer patients? new study says yes!
Symptom relief CompletedThis study looked at whether group-based cancer rehabilitation (exercise and support) works when done online versus in person for people with advanced breast or colorectal cancer. 111 adults took part in Toronto and Vancouver. The goal was to see if the virtual option is practica…
Matched conditions: ADVANCED BREAST CANCER
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Scientists check if Real-World records can stand in for clinical trials
Knowledge-focused CompletedThis study looked at health records from nearly 4,000 women with advanced breast cancer to see if they could recreate the results of a previous clinical trial called MONARCH-3. The goal was to learn when real-world data can be trusted to answer medical questions. No new treatment…
Matched conditions: ADVANCED BREAST CANCER
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Scientists check if Real-World records can replace clinical trials
Knowledge-focused CompletedThis study looked at whether information from everyday cancer clinics (real-world data) can produce the same results as a past clinical trial called MONALEESA-2 for advanced breast cancer. Researchers analyzed records from over 2,400 patients to see if the real-world data could r…
Matched conditions: ADVANCED BREAST CANCER
Sponsor: Shirley Vichy Wang • Aim: Knowledge-focused
Last updated May 11, 2026 20:48 UTC
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New drug study aims to tailor breast cancer treatment for chinese women
Knowledge-focused CompletedThis study looked at how the drug palbociclib works in Chinese women with a certain type of advanced breast cancer. 26 postmenopausal women took the drug, and researchers measured its levels in the body and checked for side effects. The goal was to gather information for Chinese …
Matched conditions: ADVANCED BREAST CANCER
Phase: PHASE1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Apr 26, 2026 19:37 UTC