ACUTE-ON-CHRONIC LIVER FAILURE

This study tests a new blood-filtering method (DPCAS+LPE) in 192 adults with acute-on-chronic liver failure and sepsis. The goal is to see if it lowers death rates at 4 and 12 weeks compared to standard plasma exchange. Participants receive two sessions of the therapy, and resear…

This study tests a new drug called F573 in people with liver injury or liver failure. The goal is to see if it is safe and how it affects the body. About 97 adults will take part, and half will get the drug while the other half gets a placebo. The study focuses on safety and does…

This study looks at how well liver transplants work for people with severe acute-on-chronic liver failure (ACLF), a life-threatening condition. Researchers will track 3,000 adults with cirrhosis who are listed for a transplant to see who survives and how different transplant type…

This study tests whether a blood-filtering device called DPMAS can improve immune function in people with acute-on-chronic liver failure. The device removes toxins and inflammatory substances from the blood. Researchers will compare 40 intensive care patients who receive either s…

This study tests whether adding a blood-filtering device called CytoSorb to standard care can help people with acute-on-chronic liver failure. The device aims to remove harmful substances like bilirubin and ammonia from the blood. Twenty adults with severe liver failure will rece…

This study is a large registry that collects data on how a blood-filtering device called CytoSorb is used in real-world intensive care settings. It will include up to 3,000 critically ill patients with conditions like septic shock, severe lung injury, or liver failure. The goal i…

This study reviews medical records of 446 people with hepatitis B-related liver failure who received stem cell therapy. The goal is to find out why some patients improve and others do not. By identifying risk factors, doctors hope to make stem cell treatment more effective in the…