New injection shows promise for liver failure in early trial

NCT ID NCT05689645

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial is testing an experimental drug called F573 in 97 people with acute liver failure or acute-on-chronic liver failure. Participants receive daily injections of F573 or a placebo for 7 days. The main goal is to check safety and side effects, while also looking at survival and liver function. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

F573 injection

What this could lead to

If successful, this could point toward a new treatment option for acute liver failure or acute-on-chronic liver failure, potentially improving survival and reducing need for transplant.

What could go wrong

This is an early Phase 2 trial with only 97 participants, so results may not apply to all patients. The drug is still experimental, and safety and effectiveness are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute liver failure Acute-On-Chronic Liver Failure drug-induced liver injury hepatitis B virus infection intrahepatic cholestasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Southwest Medical University

    RECRUITING

    Luzhou, Sichuan, China

    Contact

  • Beijing You 'an Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact

  • First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, China

    Contact

  • Heze Municipal Hospital

    RECRUITING

    Heze, Shandong, China

    Contact

  • Hunan Medical College General Hospital (formerly Huaihua City First People's Hospital)

    RECRUITING

    Huaihua, Hunan, China

    Contact

  • Pingxiang Second People's Hospital

    RECRUITING

    Pingxiang, Jiangxi P, China

    Contact

  • Qingyuan People's Hospital (Sixth Affiliated Hospital of Guangzhou Medical University)

    RECRUITING

    Qingyuan, Guangdong, China

    Contact

  • Shanxi Bethune Hospital

    RECRUITING

    Taiyuan, Shanxi, China

    Contact

  • Shiyan City Taihe Hospital

    RECRUITING

    Shiyan, Hubei, China

    Contact

  • The Affiliated Hospital of Binzhou Medical University

    RECRUITING

    Binzhou, Shandong, China

    Contact