New blood filter aims to save lives in liver failure and sepsis

NCT ID NCT06562803

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special blood-filtering device (DPCAS+LPE) in 192 adults with acute-on-chronic liver failure and sepsis. The device removes harmful inflammatory substances from the blood. Researchers will compare survival rates and organ function between patients receiving this device plus standard care versus standard care alone. The goal is to see if this approach can reduce deaths within 4 and 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

double plasma cytokine adsorption system with sequential low-dose plasma exchange (DPCAS+LPE) device

What this could lead to

If successful, this could offer a new treatment option to improve survival in patients with severe liver failure complicated by sepsis.

What could go wrong

This is a mid-stage trial with 192 participants, so results may not apply to all patients. The device is complex and carries risks like bleeding or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute-On-Chronic Liver Failure infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Third Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510630, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••