New blood filter aims to save lives in liver failure and sepsis
NCT ID NCT06562803
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a special blood-filtering device (DPCAS+LPE) in 192 adults with acute-on-chronic liver failure and sepsis. The device removes harmful inflammatory substances from the blood. Researchers will compare survival rates and organ function between patients receiving this device plus standard care versus standard care alone. The goal is to see if this approach can reduce deaths within 4 and 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- double plasma cytokine adsorption system with sequential low-dose plasma exchange (DPCAS+LPE) device
- What this could lead to
- If successful, this could offer a new treatment option to improve survival in patients with severe liver failure complicated by sepsis.
- What could go wrong
- This is a mid-stage trial with 192 participants, so results may not apply to all patients. The device is complex and carries risks like bleeding or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Third Affiliated Hospital of Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, 510630, China
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