ACUTE-ON-CHRONIC LIVER FAILURE
Clinical trials for ACUTE-ON-CHRONIC LIVER FAILURE explained in plain language.
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New blood test may reduce transfusions and complications in liver failure bleeding
Disease control CompletedThis study tested whether a special blood test (ROTEM) can better guide blood transfusions in people with acute-on-chronic liver failure who are bleeding. 262 participants were randomly assigned to receive transfusions based on either the ROTEM test or standard blood tests. The g…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: NA • Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New Blood-Cleansing device shows promise for liver crisis patients
Disease control CompletedThis study tested a new medical device called MEX-CD1 that filters the blood in people with acute-on-chronic liver failure (ACLF), a serious condition where the liver suddenly stops working. Eleven adults received three blood-filtering sessions over one week. The main goals were …
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: NA • Sponsor: Mexbrain • Aim: Disease control
Last updated May 04, 2026 16:24 UTC
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Healthy volunteers help test new liver Drug's safety
Knowledge-focused CompletedThis early-stage study tested a new drug, G1090N, in 52 healthy adults to see how the body processes it and whether it is safe. The goal was to measure drug levels in blood and urine after single and multiple doses. No treatment was given for any disease; the study simply gathere…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: PHASE1 • Sponsor: Genfit • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Study seeks best fluid strategy for liver patients with sepsis
Knowledge-focused CompletedThis study looked at 350 adults with liver cirrhosis and sepsis-induced low blood pressure to find the best way to estimate how much fluid they need. Researchers compared different methods to guide fluid therapy, aiming to improve blood pressure and reduce complications. The goal…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC