ACUTE-ON-CHRONIC LIVER FAILURE
Clinical trials for ACUTE-ON-CHRONIC LIVER FAILURE explained in plain language.
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Could stem cells offer a lifeline for sudden liver failure?
Disease control CompletedThis study investigates whether infusions of bone marrow stem cells (CG-BM1) can safely help people with acute-on-chronic liver failure, a life-threatening condition where the liver suddenly stops working. The trial involves 90 adults and will test different doses of stem cells g…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: PHASE1, PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New device aims to filter toxic iron from blood in liver failure patients
Disease control CompletedThis study tested a new medical device called MEX-CD1 in 11 adults with acute-on-chronic liver failure (ACLF), a serious condition where the liver suddenly stops working. The device works like a dialysis machine to filter excess iron from the blood. The main goals were to see if …
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: NA • Sponsor: Mexbrain • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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New blood test could save lives in liver failure bleeding emergencies
Disease control CompletedThis study tested whether a special blood test (ROTEM) can better guide blood transfusions in people with acute-on-chronic liver failure who are bleeding from enlarged veins. 262 participants were randomly assigned to receive transfusions based on either the new test or standard …
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: NA • Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New drug G1090N tested in healthy volunteers for first time
Knowledge-focused CompletedThis early-phase trial tested the safety and how the body handles a new drug called G1090N in 52 healthy adults. Participants received single or multiple doses up to 1200 mg. The goal was to measure drug levels in blood and urine, and check for side effects. This is a first step …
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: PHASE1 • Sponsor: Genfit • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Study seeks best fluid strategy for liver patients with sepsis
Knowledge-focused CompletedThis study compared different methods to estimate how much fluid is needed in patients with liver cirrhosis or acute-on-chronic liver failure who also have sepsis and low blood pressure. Researchers enrolled 350 adults and looked at whether using ultrasound-guided fluid assessmen…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:05 UTC