New blood test could save lives in liver failure bleeding emergencies

NCT ID NCT05124041

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether a special blood test (ROTEM) can better guide blood transfusions in people with acute-on-chronic liver failure who are bleeding from enlarged veins. 262 participants were randomly assigned to receive transfusions based on either the new test or standard lab tests. The goal was to see if the new approach reduces bleeding, transfusion side effects, and blood clots.

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Conditions

The condition(s) this trial relates to.

Acute-On-Chronic Liver Failure cirrhosis of liver esophageal varices with bleeding portal vein thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Postgraduate Institute of Medical Education and Research

    Chandigarh, Choose Any State/Province, 160012, India