Study seeks best fluid strategy for liver patients with sepsis
NCT ID NCT05059795
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compared different methods to estimate how much fluid is needed in patients with liver cirrhosis or acute-on-chronic liver failure who also have sepsis and low blood pressure. Researchers enrolled 350 adults and looked at whether using ultrasound-guided fluid assessment or standard goal-directed therapy leads to better outcomes, like reaching a target blood pressure. The goal is to find the safest and most effective way to guide fluid treatment in this complex group of patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Albumin + electrolyte solution
What this could lead to
If successful, this could help doctors choose the best way to give fluids to liver disease patients with sepsis, potentially improving survival.
What could go wrong
This is a completed study comparing methods, not testing a new treatment. Results may not change practice immediately or apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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PGIMER
Chandigarh, Chandigarh, 160012, India
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Postgraduate Institute of Medical Education and Research
Chandigarh, 160012, India