ACUTE DECOMPENSATED HEART FAILURE

This study tested a bedside device called the Reprieve Decongestion Management System in 100 hospitalized patients with acute decompensated heart failure. The device automatically adjusts the dose of a diuretic (furosemide) and saline based on the patient's real-time urine output…

This study tested a new device called the Doraya Catheter in 25 hospitalized heart failure patients whose bodies were not responding well to standard water pills (diuretics). The goal was to see if the catheter could safely and effectively remove excess fluid. The study focused o…

This completed study looked at 60 adults with acute decompensated heart failure and kidney impairment. Researchers compared three intravenous heart medications—levosimendan, dobutamine, and milrinone—to see which one improved heart and kidney function best. The goal was to find t…

This study tests whether starting cardiopulmonary rehabilitation (exercise and breathing training) early in the hospital helps people with acute decompensated heart failure recover faster. About 40 adults who are stable enough will take part. The goal is to see if early rehab imp…

This study tested whether adding empagliflozin (a diabetes drug) to standard diuretics helps hospitalized heart failure patients with moderate to advanced kidney disease urinate more fluid. 25 participants were given the combination, and researchers measured urine output. The goa…

This study tested whether a very high dose of the diuretic bumetanide can remove more fluid than standard doses of furosemide in people hospitalized with worsening heart failure. Twenty patients received either the ultra-high dose or the usual dose over 24 hours. The goal was to …

This study looked at whether adding manual lymphatic drainage (a gentle massage technique) to early in-hospital cardiac rehabilitation helps people with acute decompensated heart failure. The goal was to reduce leg swelling and improve physical function. Forty stable hospitalized…

This study tested a device called preCARDIA that temporarily blocks a large vein in the chest to help patients with sudden, severe heart failure. The goal was to see if it is safe and can help remove excess fluid when standard treatments are not working. The study included 60 adu…

This study observed 49 adults hospitalized with acute heart failure to learn how fluid congestion behaves during treatment. Researchers tracked clinical signs, lab tests, and ultrasound measures, then followed patients for a year to see who was readmitted or died. The goal is to …

This study tested a wearable heart monitoring patch in people recovering from a severe heart failure episode. The goal was to see if the patch could collect useful health data at home, making future drug research easier. About 54 adults wore the patch for a few days after leaving…