New device automates fluid removal in heart failure – could it be a game changer?
NCT ID NCT05174312
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a bedside device called the Reprieve Decongestion Management System in 100 hospitalized patients with acute decompensated heart failure. The device automatically adjusts the dose of a diuretic (furosemide) and saline based on the patient's real-time urine output, aiming to remove excess fluid more safely and effectively than standard care. The main goals were to see if the device increases urine sodium output and reduces complications like kidney injury or electrolyte problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Reprieve Decongestion Management System (a bedside device that automatically adjusts diuretic and saline infusion based on urine output)
What this could lead to
If successful, this device could help doctors remove excess fluid more safely and efficiently in heart failure patients, potentially reducing hospital stays and complications.
What could go wrong
This is a small, early-stage trial (100 participants) comparing a device to standard care. The device may not show clear benefits, and there are risks like kidney injury or electrolyte imbalances.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ascension Texas Cardiovascular
Austin, Texas, 78705, United States
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Atrium Health Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, 27157, United States
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Baylor Scott & White
Dallas, Texas, 75246, United States
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Cone Health
Greensboro, North Carolina, 27401, United States
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Duke University Hospital
Durham, North Carolina, 27710, United States
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Eastern Shore Research Institute
Fairhope, Alabama, 36532, United States
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MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Ohio State University Hospital
Columbus, Ohio, 43210, United States
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Prisma Health
Columbia, South Carolina, 29203, United States
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St. Louis VA
St Louis, Missouri, 63130, United States
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The Lindner Research Center at Christ Hospital
Cincinnati, Ohio, 45219, United States
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Trinity Health Ann Arbor Hospital
Ypsilanti, Michigan, 48197, United States
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University of California Irvine
Irvine, California, 92697, United States
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University of Vermont Medical Center
Burlington, Vermont, 05401, United States
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Washington University
St Louis, Missouri, 63130, United States