ACUTE CORONARY SYNDROME

This study looked at whether doing cardiac rehab at home, or a mix of home and clinic sessions, works as well as going to the clinic for all sessions. 206 heart patients participated, using a mobile health platform and home exercise. The goal was to see if flexible options could …

This completed Phase 2 trial tested whether a single daily polypill (containing a statin, aspirin, and a blood thinner) could improve medication adherence in 140 patients who had a heart attack and received a stent. The study compared the polypill to usual care with separate pill…

This study tested a combination of two drugs, rivaroxaban and ticagrelor, in 40 patients with atrial fibrillation who had a stent placed. The goal was to see if this combo causes less bleeding and prevents heart attacks or strokes better than current treatments. Patients took the…

This study tested the Xience Sierra stent in 1757 patients with complex heart conditions, including those with diabetes or prediabetes. The stent is a small mesh tube used to open blocked arteries. Researchers tracked heart-related deaths, heart attacks, and the need for repeat p…

This study tested whether evolocumab (Repatha), a drug that lowers LDL cholesterol, can reduce inflammation and improve heart function in people who recently had a mild heart attack (NSTEMI). Sixty participants received either evolocumab or a placebo within 24 hours of admission.…

This study looked at 190 adults who had a heart attack (acute coronary syndrome) to see if moderate-dose statins lower bad cholesterol as effectively as high-dose statins. After 3 months, researchers measured how many patients reached a 50% or greater drop in LDL cholesterol. The…

This study tested whether taking aspirin twice a day (200 mg total) works better than the standard once-daily dose (100 mg) to prevent another heart attack, stroke, or urgent heart procedure in diabetic patients who recently had a heart attack. About 2,500 participants were follo…

This study tested whether colchicine, a drug used for gout, can reduce inflammation in the arteries of people with diabetes who recently had a heart attack or stroke. Researchers used a special PET scan to measure inflammation in the blood vessels. 115 participants were randomly …

This study tested whether a simple bedside heart ultrasound measurement, called the S' wave, can help emergency doctors quickly identify acute coronary syndrome (heart attack or unstable angina) in patients with chest pain. Researchers enrolled 66 adults who came to the ER with c…

This study tested whether a non-invasive technique called remote ischemic preconditioning (RIPC) can prevent kidney damage caused by contrast dye used in heart imaging. The procedure involves briefly inflating a blood pressure cuff on the arm to restrict blood flow in cycles. Res…

This study followed over 1,000 people who had a heart attack and were given a quick-acting intravenous blood thinner called cangrelor during a procedure to open blocked arteries. Researchers wanted to see how often bleeding occurred when patients then switched to a different oral…

This completed study looked at how levels of C-reactive protein (CRP), a marker of inflammation, change in 35 patients having emergency angioplasty for a heart attack. Researchers took blood samples before the procedure and at several time points up to 30 days after. The goal was…

This completed study looked at 1,000 heart attack patients to understand why some have no standard risk factors like smoking, high blood pressure, or diabetes. Researchers compared these 'SMuRF-less' patients to those with risk factors, examining their medical history, lab tests,…

This study looked at 1,655 people who had a heart attack or unstable angina (acute coronary syndrome) to create a personalized risk model. Researchers used medical tests, genetic information, and other health data to predict who might have worse outcomes or complications from tre…

This study combined data from over 5,000 people to see if a simple blood test (troponin) and risk scores used by paramedics can accurately identify those having a heart attack before they reach the hospital. The goal is to improve how patients are triaged and treated early. No ne…

This study tested whether a heart rehab program that mixes telehealth sessions with a few clinic visits is possible for people who survived a heart attack. Ten people took part, and researchers looked at how many signed up and how many completed the sessions. The goal was to see …

This study looked at how long people who had a heart attack should take two blood-thinning medicines (aspirin plus a second drug). About 5,000 patients were randomly assigned to shorter or longer treatment. The goal was to find the best balance between preventing another heart at…

This completed study looked at whether patients hospitalized for a heart attack, stroke, or other cardiovascular event received the right medications to prevent future problems. Researchers reviewed records of 129 patients to see if doctors prescribed cholesterol-lowering drugs a…