Zika virus infectious disease

This early-stage trial tested an inactivated Zika virus vaccine (VLA1601) in 150 healthy adults aged 18-49. Participants received two doses, and researchers monitored side effects and immune responses. The goal was to find the safest and most effective dose, including combination…

This study tested Moderna's experimental Zika vaccine, mRNA-1893, in 808 healthy adults aged 18 to 65. Participants received one of two doses or a placebo, and researchers monitored side effects and immune responses. The goal was to confirm the vaccine's safety and ability to pro…

This study tested whether sending health tips via WhatsApp could help families in Colombia prevent dengue, Zika, and chikungunya. About 900 households were split into three groups: one got WhatsApp messages plus community support, one got community support only, and one got routi…

This study looked at whether a single dose of the TV003 dengue vaccine or a past Zika infection could protect people from getting infected with Zika virus again. 27 healthy adults took part. Researchers gave them the vaccine or used people who had Zika before, then exposed them t…

This study tested a clever way to prevent dengue fever: releasing mosquitoes infected with Wolbachia bacteria into neighborhoods in Brazil. Over four years, researchers compared areas that got these special mosquitoes plus usual control methods to areas with usual methods alone. …

This study tested whether spraying insecticide on indoor walls (Targeted Indoor Residual Spraying) can prevent diseases spread by Aedes mosquitoes, like dengue, chikungunya, and Zika. Over 4,400 children aged 2 to 15 in Merida, Mexico took part. Researchers tracked how many got s…

This large study tested a device called Mosquito Shield that releases a repellent (transfluthrin) to keep mosquitoes away. Nearly 7,000 children aged 4-16 in Sri Lanka took part. The goal was to see if the device reduces infections from viruses like dengue. Researchers tracked in…

This study followed 775 healthy children aged 2-9 in Cambodia over three years to learn how mosquitoes spread dengue and other viruses. Researchers took blood samples every wet and dry season to check for past or current infections. The goal was to understand why young children g…

This completed study observed nearly 27,000 pregnant women in French Caribbean departments during the 2016 Zika epidemic. Researchers tracked Zika infections and their impact on pregnancy, including rates of microcephaly and other fetal abnormalities. The goal was to better under…