Moderna's zika vaccine shows promise in Mid-Stage trial
NCT ID NCT04917861
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested Moderna's experimental Zika vaccine, mRNA-1893, in 808 healthy adults aged 18 to 65. Participants received one of two doses or a placebo, and researchers monitored side effects and immune responses. The goal was to confirm the vaccine's safety and ability to produce antibodies against the Zika virus.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mRNA-1893 Zika vaccine
- What this could lead to
- If successful, this could lead to a safe and effective vaccine to prevent Zika virus infection, protecting people in affected regions.
- What could go wrong
- This is a Phase 2 trial focused on safety and immune response, not yet proving the vaccine prevents disease. Results may not guarantee effectiveness in real-world settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Benchmark Research - Fort Worth
Fort Worth, Texas, 76135, United States
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Carribean Medical Research
San Juan, PR, 00918, Puerto Rico
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Clinical Research Puerto Rico, Inc.
Guayama, PR, 00784, Puerto Rico
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Clinical Research Puerto Rico, Inc.
San Juan, PR, 00909, Puerto Rico
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GCM Medical Group, PSC
San Juan, PR, 00917, Puerto Rico
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Johnson County Clin-Trials
Lenexa, Kansas, 66219, United States
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Latin Clinical Trial Center, Inc.
San Juan, PR, 00909, Puerto Rico
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Meridian Clinical Research (Sioux City, IA)
Sioux City, Iowa, 51106, United States
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Ponce Medical School Foundation, Inc.
Ponce, PR, 00713, Puerto Rico
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Ponce Medical School Foundation, Inc.
Ponce, PR, 00716, Puerto Rico
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University of Puerto Rico
San Juan, PR, 00935, Puerto Rico
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