Modernatx, Inc.

This study is testing updated versions of Moderna's COVID-19 vaccine designed to protect against newer virus variants. It will enroll about 1,144 people, including adults, older adults, and children with certain health risks, to see how well the new shots trigger an immune respon…

This study is testing a new mRNA vaccine designed to protect against a potential bird flu pandemic. It will enroll 4,000 healthy adults to see how well their immune systems respond to two doses of the vaccine and to check for side effects. The goal is to see if this vaccine could…

This early-stage study is testing a new mRNA vaccine designed to prevent Epstein-Barr virus (EBV) infection. Researchers will enroll 120 healthy adults aged 18-30 to check if the vaccine is safe and triggers an immune response. The trial will compare two different injection metho…

This study is testing updated versions of Moderna's COVID-19 vaccine designed to match current virus variants. It will enroll about 832 people aged 65 and older, or those 12-64 with health conditions that put them at high risk for severe COVID-19. The main goals are to see how we…

This study continues testing mRNA-3705 in people with methylmalonic acidemia (MMA), a rare genetic disorder. It follows patients who previously received this experimental treatment in earlier studies to check long-term safety and effectiveness. The goal is to see if continued tre…

This study is testing the safety and early effectiveness of an experimental mRNA injection called mRNA-1195 in adults with early-stage multiple sclerosis (MS). Researchers will give different doses or a placebo to 180 participants and monitor them for side effects and changes in …

This study is testing an investigational mRNA therapy called mRNA-3927 for people with propionic acidemia (PA), a rare and serious genetic disorder. The goal is to find a safe and effective dose that can reduce dangerous metabolic crises and improve health. The study will enroll …

This early-stage trial is testing the safety and effectiveness of an experimental mRNA cancer vaccine called mRNA-4359. It will be given alone and combined with approved immunotherapy drugs to 361 adults with advanced solid tumors like melanoma and lung cancer. The main goals are…

This study is testing a new mRNA-based therapy called mRNA-2808 for people with multiple myeloma that has come back or stopped responding to standard treatments. The main goals are to find a safe dose and see how well the body handles the treatment. Researchers will also check if…

This study follows people with propionic acidemia who were in an earlier trial of the experimental treatment mRNA-3927. It aims to check the long-term safety of continuing this treatment and see if it helps control the disease. About 50 participants will receive the same dose the…

This study aims to see how well two updated Moderna COVID-19 vaccines work to prevent symptomatic infection in healthy adults aged 50 to 64. It will enroll 30,000 participants who do not have high-risk medical conditions. Some participants will receive one of the new vaccine form…

This study aims to learn more about propionic acidemia, a rare genetic disorder, by looking back at the medical records of 60 patients. Researchers will collect information about how often patients experience serious health events called metabolic decompensations and related hosp…