Modernatx, Inc.

This clinical trial is testing an experimental mRNA vaccine, called mRNA-1647, designed to prevent infection with cytomegalovirus (CMV). The study will enroll about 873 healthy participants between the ages of 9 and 25 to see if the vaccine is safe and if it triggers a strong imm…

This is the first human study of Moderna's experimental mRNA vaccine designed to protect against Epstein-Barr virus (EBV), which causes mononucleosis and is linked to several cancers. The trial will test the vaccine's safety and how well it triggers an immune response in 482 heal…

This large, late-stage study is testing an experimental mRNA vaccine designed to prevent norovirus, a common cause of severe stomach flu. It will enroll over 37,000 adults to see if the vaccine is safe and if it can stop moderate or severe cases of vomiting and diarrhea caused by…

This study is testing the safety and immune response of two new mRNA vaccines in healthy infants. One vaccine targets both RSV and human metapneumovirus, while the other targets RSV alone. The goal is to see if these vaccines are safe and can help protect young children from thes…

This study is testing two new mRNA vaccines, mRNA-1403 and mRNA-1405, designed to prevent norovirus, a common cause of severe stomach flu. It will involve about 1,400 healthy adults aged 18 to 80 to check if the vaccines are safe and if they trigger a good immune response. The re…

This is an early-stage safety study testing a new mRNA-based cancer therapy called mRNA-4106. It is being given alone and in combination with standard immunotherapy drugs to 57 patients with various advanced solid tumors. The main goal is to find a safe dose and understand the si…

This early-stage study is testing a new mRNA-based drug called mRNA-3745 for people with a rare inherited condition called glycogen storage disease type 1a (GSD1a). The main goal is to see if the drug is safe and well-tolerated when given through an IV. Researchers will also chec…

This study is testing an experimental mRNA therapy called mRNA-3705 for people with a rare genetic disorder called methylmalonic acidemia (MMA). The main goals are to see if the treatment is safe and if it can lower the high levels of a harmful acid in the blood that causes the d…

This study is testing whether adding a personalized cancer vaccine to standard immunotherapy helps prevent melanoma from returning after surgery. It involves 267 people with high-risk melanoma who have had their cancer completely removed. The goal is to see if the combination tre…

This early-stage study is testing the safety and immune response of a personalized mRNA vaccine called mRNA-4157 in people with solid tumors. The vaccine is being tested alone and in combination with standard treatments like chemotherapy and immunotherapy. The goal is to see if t…

This study is testing an investigational mRNA vaccine designed to protect against Respiratory Syncytial Virus (RSV). The vaccine is given to pregnant women to see if it is safe and if it helps create protective antibodies that can be passed to their babies. Researchers will monit…

This study is testing a new RSV vaccine booster shot from Moderna. It's for adults aged 60 and older who received an RSV vaccine (Arexvy or Abrysvo) at least a year ago. The main goals are to see how safe the booster is and how well it strengthens the body's defenses against RSV.

This early-stage study aims to check if a new Moderna drug called mRNA-0184 is safe for people. Researchers will give the drug to 52 healthy volunteers and watch for any side effects. They'll also measure how the drug moves through the body and what effects it has.